Abstract：Objective To analyze the survival time of HIV/AIDS patients who initially received antiretroviral treatment and its influencing factors in Yancheng City during 2005-2015. Methods The data about HIV/AIDS patients’ survival time and death in Yancheng City during 2005-2015 were collected from Chinese HIV/AIDS Integrated Control System. Life table method was employed to calculate the survival rate of the patients, and Cox proportional hazard regression model was used to analyze the factors possibly affecting the survival time. Results A total of 670 HIV/AIDS patients receiving antiretroviral therapy were enrolled in this study, and 48 (7.16%) patients died of AIDS-related illness at the end of the study. The cumulative survival rates of antiretroviral treatment after 1, 2, 3, 4 and 5 years were 0.93, 0.91, 0.91, 0.88 and 0.88 respectively. The Results of multivariate Cox proportional hazard regression model analysis indicated that HIV/AIDS cases aged 25-<50 years at the first diagnosis had a lower mortality risk than those ≥50 years (HR=0.350, 95%CI:0.196-0.625, P<0.001), and the cases with lower CD4+ T cell count of < 50/mm3 at baseline had a higher mortality risk than those with CD4+ T cell count of 50-<200/mm3 and ≥200/mm3 (HR=0.447, 95%CI:0.216-0.925, P=0.030; HR=0.286, 95%CI:0.148-0.552, P<0.001). Conclusions Age at first diagnosed HIV-positive and CD4+ T cell count at baseline affect the survival time of HIV/AIDS patients, indicating that the coverage of HIV surveillance and testing needs to be expanded, and early diagnosis and early treatment of HIV/AIDS are the key to improve thepatients, survival rate.
2018, Vol. 25 
