Epidemiological survey on a family clustering of human infection with avian influenza A (H7N9) virus and one-year follow-up study on the survival case in Yantai City
XU Xiao-wen, JIANG Mei, SUN Zhen-lu, MOU Xiao-dong, LIU Tao, LIU Jing-yu
Yantai Municipal Center for Disease Control and Prevention, Yantai, Shandong 264003, China
Abstract：Objective To analyze the epidemic situation of the first family cluster of two patients with avian influenza A (H7N9) infection in Yantai City, and to investigate the clinical consequence in the recovery phase. Methods A field investigation was conducted to collect epidemiological information of the two cases. The survival case was followed-up, and the reexamination Results in the first, third, sixth and twelfth months after the onset of the disease were compared and analyzed. Results The index case (a father), with a history of recent live poultry exposure, later died despite medical treatment. His son was thus recognized as the close contact survived. One month after the onset of the disease, the survival patient’s reexamination Results of routine blood test, liver function test and ultrasonic cardiogram (UCG) were all normal. Six months after the onset of the disease, the subjective symptoms disappeared and no abnormal lung sound was heard on auscultation. In the first year of the onset, arrhythmia persisted and pulmonary functions gradually improved. Pulmonary lesions were absorbed gradually, but scanty amount of shadows of fibrotic streaks in lung still could be discovered. Conclusions It is the first family cluster of avian influenza A (H7N9) infection in Yantai City. Our findings indicate that the index case is likely to acquire virus infection from poultry or to transmit virus to his son. The liver and lung injury induced by H7N9 virus infection in human beings can be restored gradually, but the recovery of arrhythmia remains to be further observed.
徐小雯, 姜梅, 孙振璐, 牟晓东, 刘涛, 刘靖宇. 烟台市一起家庭聚集性人感染H7N9禽流感疫情调查及存活病例1年随访分析[J]. 实用预防医学, 2018, 25(2): 212-214.
XU Xiao-wen, JIANG Mei, SUN Zhen-lu, MOU Xiao-dong, LIU Tao, LIU Jing-yu. Epidemiological survey on a family clustering of human infection with avian influenza A (H7N9) virus and one-year follow-up study on the survival case in Yantai City. , 2018, 25(2): 212-214.
2018, Vol. 25 
