Cross-sectional analysis on smoking and alcohol consumption, aminotransferase and treatment history of participants with 30-year follow-up of the Qidong Hepatitis B Intervention Study
YAN Yong-feng*, CHEN Tao-yang, YAO Hong-yu, FAN Chun-sun, LU Ling-ling, LU Jian-hua, NI Zheng-ping, HUANG Fei, WANG Yu-ting, QU Chun-feng, ZHANG Ya-wei
*Department of Etiology, Qidong Liver Cancer Institute, Qidong People’s Hospital, Qidong, Jiangsu 226200, China
Abstract:Objective To investigate the socio-demographic characteristics, smoking and alcohol consumption and disease history of cohort participants with the marriage age from Qidong Hepatitis B Intervention Study (QHBIS). Methods A cross-sectional study was conducted among QHBIS participants from January to October in 2013, and the objects in the vaccine group and the control group were sampled by randomly stratified method. A self-designed questionnaire was used to collect the objects’ general information, personal habit, disease history and other data. Results A total of 8,423 participants were followed-up. The males in the vaccine group and the control group accounted for 47.61% and 46.62% respectively, and no statistically significant difference was found in the gender distribution between the two groups (χ2=0.833, P=0.362). The prevalence rates of current smoking in the males of the two groups were 48.36% and 48.12% respectively, showing no statistically significant difference (χ2=0.022, P=0.883). The prevalence rate of male alcohol consumption was lower in the vaccine group than in the control group (22.84% vs. 28.87%), with a statistically significant difference (χ2=18.844, P<0.001). The results of disease history survey revealed that 2.86% and 5.50% research objects in the two groups respectively had a history of elevated aminotransferase, showing a statistically significant difference (χ2=37.274,P<0.001). 1.18% and 2.13% research objects in the two groups respectively received anti-hepatitis B viral therapies, with a statistically significant difference (χ2=7.124, P=0.008). Conclusions We collect the important information regarding smoking and drinking habits, aminotransferase and history of hepatitis B treatment of QHBIS participants through this cross-sectional study, and the results provide reliable resources for exploring the etiology of liver cancer and other chronic diseases. It is necessary to optimize the design and implementation of the questionnaire so as to obtain more accurate epidemiological information.
严永锋, 陈陶阳, 姚红玉, 樊春笋, 陆玲玲, 陆建华, 倪正平, 黄飞, 王宇婷, 曲春枫, 张亚玮. 启东乙肝干预研究30年随访人群烟酒嗜好、转氨酶及治疗史的横断面分析[J]. 实用预防医学, 2018, 25(1): 23-26.
YAN Yong-feng, CHEN Tao-yang, YAO Hong-yu, FAN Chun-sun, LU Ling-ling, LU Jian-hua, NI Zheng-ping, HUANG Fei, WANG Yu-ting, QU Chun-feng, ZHANG Ya-wei. Cross-sectional analysis on smoking and alcohol consumption, aminotransferase and treatment history of participants with 30-year follow-up of the Qidong Hepatitis B Intervention Study. , 2018, 25(1): 23-26.