Abstract:Objective To compare the knowledge awareness, attitude and practice of smear positive tuberculosis (TB) patients before and after one-to-one health education, to analyze the factors influencing the knowledge awareness rate, and to put forward specific proposals. Methods Questionnaire surveys were conducted before and after the intervention. The categorical data were described by the number of cases and constituent ratios. Chi-square (χ2) test was used for single factor analysis, and logistic regression for multiple-factor analysis. Results After the intervention, the awareness rates of 14 knowledge points were higher than before, but the awareness rate of 1 knowledge point was lower. The total awareness rate of all knowledge points rose from 37.17% to 49.09%, with statistically significant differences (χ2=13.431, P=0.000). Logistic regression analysis showed that the factors influencing knowledge awareness of smear positive TB patients included place of residence , marital status and medical insurance. The awareness rate was higher in rural areas than in urban areas (OR=1.862), lower in the divorced(OR=0.084) and the widowed (OR=0.236) than in the married, higher in patients with urban residents’ medical insurance (OR=3.513)or with urban workers’ medical insurance(OR=1.919) than in the patients with self-paying medical expense. Conclusions The awareness rate of prevention and treatment knowledge in smear positive TB patients is improved through the health education. The knowledge awareness is affected by place of residence, marital status and medical insurance.