[1] Park YJ,Chang HK,Park DJ,et al. Polymorphism in the promoter and exon 1 of the cytotoxic T lymphocyte antigen-4 gene associated with autoimmune thyroid 2 disease in Koreans[J]. Thyroid, 2000,1(6):453-459. [2] Cho IL,Chung JH,Kim IS,et al. Lack of a genetic association between the CTLA-4 gene and Graves’disease in Koreans[J].Thyroid,2006,16(3):23-29. [3] Khalilzadeh O, Mojazi Amiri H, Tahvildari M, et al Pretibial myxedema is associated with polymorphism in exon 1 of CTLA-4 gene in patients with Graves' ophthalmopathy [ J ]. Arch Dermatol Res ,2009 , 301( 10) : 719-723 . [4] Tomer Y, Greenberg DA, Barbesino G, et al. CTLA-4 and not CD28 is a susceptibility gene for thyroid autoantibody production. J Clin Endocrinol Metab, 2001, 86 :1687 - 1693. [5] . Zaletel K, Krhin B, Gaberscek S, et al.The influence of the exon 1 polymor- phism of the cytotoxic T lymphocyte antigen 4 gene on thyroid antibody production in patients with newly diagnosed Graves’disease . Thyroid, 2002, 12 (5) : 373-376. [6] .Basolo F, Caligo MA, Pinchera A,et al.Cyclin D1 overexpression in thyroid carcinomas: relation with clinico-pathological parameters, retinoblastoma gene product, and Ki67 labeling index.Thyroid, 2000,10(9):741-746. [7] . Chen W, Jin W, Wahl SM. Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells[J].J Exp Med,1998,188(10), 1849-1857.
2015, Vol. 22 
