Abstract：Objective To analyze the serotype distribution and antibiotic resistance of Salmonella from patients with infectious diarrhea in Guangzhou. Methods The serotype of 566 strains of Salmonella isolated in 2012、2013 from 8 monitoring hospitals was determined by serology agglutinating method,Antimicrobial susceptibility was determined by disk diffusion method(KB) in accordance with Clinical and Laboratory Standards Institute procedures. Results 566 strains of Salmonella consisted of 62 serotypes, of which 235 strains were Salmonella typhimurium (41.52 %) , 89 strains were Salmonella enteritidis (15.72%), 45 strains were Salmonella Stanley (7.95%). Antimicrobial susceptibility tests showed that the resistance was most frequently detected to Cephalosporin (85%), followed by ciprofloxacin (75.44%), and the resistance was also observed with Ampicillin, Peptidylsulfanilamide, tetracycline, nalidixic acid (60%). Among the 566 isolates, strains resistant to three or more antibiotics are the most(71.02%),followed by ACSSuT + drug-resistant spectrum (multi-resistant to ampicillin, chloramphenicol, streptomycin, Peptidylsulfanilamide, tetracycline or more drugs ) (27.39%).The rate of resistant to ACSSuT + of Salmonella typhimurium is 44.68%. ConclusionsSalmonella typhimurium and Salmonella enteriditics are the main serotypes. It is notable that the resistance rate of Salmonella to cephalosporins and multiple drug increasing recently, especially Salmonella typhimurium .
2016, Vol. 23 
