Abstract：Objective To analyze and compare the epidemic features of measles in the high-occurrence, low-occurrence and rebound stages in Luogang District, Guangzhou City from 2005 to 2014 so as to provide scientific evidence for formulating measles prevention and control strategies.Methods We analyzed and compared the incidence and epidemic characteristics of measles in the three stages based on measles surveillance data from Infectious Disease Information Reporting and Management System, Measles Ssurveillance Information Reporting and Management System and archival materials concerning measles case information from 2005 to 2014.Results A total of 269 measles cases were reported in Luogang District, Guangzhou City in 2005-2014, with the annual average incidence rate of 8.26/100,000. The high-occurrence stage, the low-occurrence stage and the rebound stage were found in the periods of 2005-2008, 2009-2012 and 2013-2014 respectively, and the annual average incidence rates of measles in the 3 stages were 15.39/100,000, 1.26/100,000 and 8.02/100,000 respectively. In March to June each year, there was a peak for measles incidence in both high-occurrence and rebound stages. In December to next January, there was another peak in the rebound stage. No obvious measles incidence peak was found in the low-occurrence stage, but there were cases reported in April each year. The main involved age group gradually changed from the targeted population for vaccination aged 8 months to 14 years in the high-occurrence stage to the population aged < 8 months and >14 years in the rebound stage, and there were statistically significant differences in the age distribution among the 3 stages (χ2=14.583, P=0.006). As for the occupation distribution of the cases, scattered children ranked the first in all the three stages, and students and preschoolers ranked the second and the third respectively in the high-occurrence stage, while workers ranked the second in the low-occurrence and rebound stages. Of the cases reported in all the stages, more than 50% were floating population, but the proportion of permanent residents increased in the rebound stage (χ2=11.295, P=0.004). No statistically significant differences were found in the distribution of gender, vaccination history and medical institution exposure 7-21 days before measles onset among the three stages (P<0.05). Conclusions The epidemic of measles in Luogang District, Guangzhou City from 2005 to 2014 experiences high-occurrence, low-occurrence and rebound stages. The incidence peak each year, the distribution of age, occupation and floating population in measles epidemic are significantly different among the three stages. It is necessary to take targeted prevention and control measures based on the epidemiological characteristics of different stages of measles.
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2016, Vol. 23 
