Research progress in circadian rhythm disruption and infertility
ZHAO Mengjie1, ZONG Zhiqiang2, WANG Xinchen2, TANG Ying3
1. School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China; 2. School of Nursing, Anhui Medical University, Hefei, Anhui 230032, China; 3. The Second Clinical College, Anhui Medical University, Hefei, Anhui 230032, China
Abstract:The incidence rate of infertility has been increasing in recent years, and it has become a vital medical and social problem in both developed and developing countries. Infertility not only has an adverse impact on couple’s physical and mental health, but also causes a range of social problems, such as domestic violence and social barriers. The existing evidence indicates that infertility is influenced by multiple factors such as genetic factors, environmental factors and adverse behaviors. With the development of society, working patterns like overtime and shift are gradually becoming common, and the frequency of using electronic products at nighthave increased significantly, which will cause circadian rhythm disruption (CRD). Relative studies have found that CRD is closely related to the incidence of infertility. This study reviews the association of CRD with infertility and its possible mechanisms, and provides new thoughts for infertility prevention andtreatment.
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