Relationship between blood glucose level and noise-induced hearing loss in noise-exposed workers
YE Pin-kai1, XIE Xue-yan2, WANG Shou-yu1
1. School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211100, China; 2. The People's Hospital of Ningguo City, Xuancheng, Anhui 242300, China
Abstract：Objective To investigate the effect of interaction between blood glucose and gender on noise-induced hearing loss (NIHL). Methods A case-control study was conducted to inquire and investigate the general information, occupational history, past history and occupational health monitoring data of workers exposed to noise. Univariate analysis was performed. Logistic regression model was used to analyze the factors influencing NIHL, and then multiplicative interaction analysis was conducted. Results Among 1,628 noise-exposed workers surveyed, 616 (37.84%) suffered from NIHL,The risk factors for NIHL were high blood glucose (OR=1.960, 95%CI:1.345-2.855), male (OR=4.346, 95%CI:2.866-6.590), high environmental noise intensity (OR=1.036, 95%CI:1.016-1.056), high monocyte count (OR=8.522, 95%CI:3.054-23.776) and low platelet count (OR=0.997, 95%CI:0.994-0.999). The risk of NIHL in workers with high blood glucose was 1.960 times that of normal blood glucose (P<0.01), and the risk of NIHL in males was 4.346 times that of females (P<0.01). The risk of NIHL increased 1.036 times for each unit increase in the intensity of environmental noise. The additive interaction between high blood glucose and male on NIHL was statistically significant, and the values of odds ratio and synergy index were 8.962 and 2.123, respectively. Conclusion It is necessary to build fasting blood glucose examination into routine examination items of thenoise-exposed workers, strengthen the surveillance on blood glucose level of male noise-exposed workers, screen out workers with high blood glucose and give certain control and intervention, and transfer out of their post if necessary.
叶品凯, 谢学艳, 王守宇. 噪声作业工人血糖水平与噪声性听力损失的关系[J]. 实用预防医学, 2022, 29(10): 1222-1225.
YE Pin-kai, XIE Xue-yan, WANG Shou-yu. Relationship between blood glucose level and noise-induced hearing loss in noise-exposed workers. , 2022, 29(10): 1222-1225.
[1] Wan JY,Cataby C,Liem A,et al. Evidence for gene-smoking interactions for hearing loss and deafness in Japanese American families[J]. Hear Res, 2020, 387:107875. [2] 王欣, 曾强, 唐慧晶,等. 2006—2015年天津市职业性噪声聋流行趋势及影响因素[J]. 公共卫生与预防医学,2017,28(2):38-41. [3] Spankovich C, Le Prell CG, Lobarinas E, et al. Noise history and auditory function in young adults with and without type 1 diabetes mellitus[J]. Ear Hear, 2017, 38(6):724-735. [4] 丰薇薇, 李碧燕. 噪声作业人员血糖水平与听力损失的关系[J]. 职业与健康,2017,33(3):419-421. [5] 白璐, 王红, 杨红艳,等. 噪声性听力损失影响因素logistic分析[J]. 中华劳动卫生职业病杂志,2018, 36(12):918-921. [6] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2017年版)[J]. 中国实用内科杂志,2018,38(4):292-344. [7] 中国高血压防治指南修订委员会,高血压联盟(中国,中华医学会心血管病学分会中国医师协会高血压专业委员会,中国医疗保健国际交流促进会高血压分会,等.中国高血压防治指南(2018年修订版)[J]. 中国心血管杂志,2019,24(1):24-56. [8] Masterson EA, Deddens JA, Themann CL, et al. Trends in worker hearing loss by industry sector, 1981-2010[J]. Am J Ind Med, 2015,58(4):392-401. [9] Enqi W,Huanhu Z,Ritu W,et al. Age-stratified comparative analysis of the differences of gut microbiota associated with blood glucose level[J]. BMC Microbiol, 2019,19(1):111. [10] 尹仕红. 不同年龄空腹血糖水平和校正血钙浓度分析[J]. 实用糖尿病杂志,2016,12(1):18-19. [11] Jang TW,Kim BG,Kwon YJ,et al. The association between impaired fasting glucose and noise-induced hearing loss[J]. J Occup Health, 2011,53(4):274-279. [12] 王霞, 闫炎, 张彤,等. 噪声暴露人员血压血糖水平与听力损失的关系[J]. 听力学及言语疾病杂志,2014,22(2):197-200. [13] Chung SS, Ho EC, Lam KS, et al. Contribution of polyol pathway to diabetes-induced oxidative stress[J]. J Am Soc Nephrol, 2003,14(8 Suppl 3):S233-S236. [14] 刘新霞, 陆垚, 刘浩中,等. 外周血白细胞端粒相对长度与噪声性听力损失的相关性研究[J]. 癌变·畸变·突变,2017,29(3):222-225,234. [15] 姜晋, 胡建安, 吴鑫,等. 某高校毕业生用耳习惯与听力损失的关系[J]. 实用预防医学,2020,27(8):923-926. [16] 马效东, 杨子娟, 侯丽明,等. 职业病危害因素联合作用对劳动者健康的影响[J]. 职业与健康,2013,29(8):900-902.
2022, Vol. 29 
