Abstract：Objective To explore the interactive effect of sex and high protein intake on fracture in Haikou youth population, and to provide a reference basis for prevention and treatment of fracture. Methods We selected 1,816 young and middle-aged adults at the age of 18-50 years in Haikou City to serve as the subjects of a questionnaire survey, and collected the general demographic characteristics, dietary frequency and previous fracture information. SPSS21.0 software was used to perform χ2 test and non-conditional logistic regression analysis of the impact of gender, high protein intake and their interaction effect on the fracture risk. Results There were 224 self-reported fracture subjects in the 1,816 respondents, with an incidence rate of 12.33%. The incidence rate of fracture in males and females was 17.15% (n=137) and 8.55% (n=87) respectively. The incidence rate of fracture in subjects with highprotein intakeper daywas 9.88% (n=81), and that in subjectswith lowprotein intakeper daywas 14.36% (n=143), showing a statistically significant difference (P<0.05). The results of multivariate logistic regression analysis revealed that after adjusting forfactors such asage, education background, economic situation, body mass index and diet, males (OR=2.233, 95%CI:1.674-2.980) and non-daily protein intake (OR=1.560, 95%CI:1.162-2.096) could increase the fracture risk in the young and middle-aged (P<0.05). Interaction effect analysis showed that there was a multiplication interaction effect between gender and daily protein intake on the fracture risk of the young and middle-aged (OR=2.412, 95%CI:1.794-3.242), but no additive effect was found. Conclusion This study finds that males and non-daily protein intake are risk factors for fracture in the young and middle-aged; moreover, sex and daily protein intake have a multiplicative interaction with the fracture risk in the young and middle-aged.
李洁洁, 陈育婵, 张云霄, 周静, 曹文婷. 海口青壮年人群性别及高蛋白摄入对骨折的交互作用[J]. 实用预防医学, 2023, 30(7): 806-809.
LI Jiejie, CHEN Yuchan, ZHANG Yunxiao, ZHOU Jing, CAO Wenting. Interaction effect of sex and high protein intake on fracture among young and middle-aged people in Haikou. , 2023, 30(7): 806-809.
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2023, Vol. 30 
