Abstract：Objective To establish a method for the determination of 2,4-D and bentazone in drinking water by on-line solid phase extraction coupled with ultra-performance liquid chromatography-tandem mass spectrometry (on-line SPE-UPLC-MS/MS). Methods After adding the internal standard, the water sample was filtered by millipore filtration. The water sample was to be mixed in the proportion ofsample water topure water being 1:3, and then concentrated and detected by on-line SPE-UPLC-MS/MS. The sample was concentrated by SPE on a C18 column, separated on a C18 column with acetonitrile-water-formic acid as the mobile phase gradient elution, and detected by multiple reaction monitoring (MRM) acquisition under anion mode. Results The linear relationships of 2,4-D and bentazone were good in the ranges of 5.00-200 ng/L and 10.0-400 ng/L,respectively, with the correlation coefficients of more than 0.9990. The method detection limits were 2 ng/L and 3 ng/L, and the recoveries were 91.2%-95.4% and 96.0%-104%, respectively. Conclusion The method is simple, sensitive, rapid, accurate and reliable; and hence, it is applicable to the trace determination of 2,4-D and bentazone in drinking water.
郑磊, 李宏亮, 闵巍, 詹铭. 在线固相萃取-超高效液相色谱-串联质谱测定饮用水中2,4-滴和灭草松[J]. 实用预防医学, 2022, 29(3): 303-306.
ZHENG Lei, LI Hong-Liang, MIN Wei, ZHAN Ming. Determination of 2,4-D and bentazone in drinking water by on-line SPE-UPLC-MS/MS. , 2022, 29(3): 303-306.
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2022, Vol. 29 
