Detection results of viral nucleic acid in 39 confirmed COVID-19 cases in Chenzhou City
LIU Ge-qun1,3, BAI Li-qiong2,3, XIAO Jun1, LI Cheng-hua1, DUAN Liang-song1, TAN Hui1, ZHENG Wen1
1. Chenzhou Municipal Center for Disease Control and Prevention, Chenzhou, Hunan 423000, China;
2. Hunan Institute for Tuberculosis Control, Changsha, Hunan 410013, China;
3. School of Public Health, Central South University, Changsha, Hunan 410078, China
Abstract：Objective To analyze the detection of viral nucleic acid at different stages of the disease and in different types of specimens in 39 confirmed COVID-19 cases in Chenzhou City, and to provide a scientific basis for clinical diagnosis, treatment and management of COVID-19. Methods Thirty-nine confirmed COVID-19 cases during the epidemic period of COVID-19 in Chenzhou City served as the research subjects. The relevant information of viral nucleic acid detection in the process of diagnosis, hospitalization and post-hospital rehabilitation management was collected to describe the detection results at different stages of the disease and in different types of specimens. Results During the COVID-19 epidemic, a total of 301 nucleic acid tests were completed for 39 confirmed cases of COVID-19 in Chenzhou City. COVID-19 cases were confirmed by nucleic acid test of throat swab specimens alone, and the combined specimen test was mainly used for follow-up after discharge. The positive rate of retesting viral nucleic acid after discharge was 12.82%. Conclusions Increasing the number of nucleic acid test and combined test of different specimens at the same stage can improve the positive detection rate of specimens. It is necessary to conduct further research on re-positive cases of nucleic acid test in discharged patients with COVID-19, and strengthen health management.
2021, Vol. 28 
