Abstract：Objective To explore the epidemiological characteristics, pathogens, clinical symptoms and other characteristics ofhand, foot, and mouth disease (HFMD) and herpangina. Methods Descriptive epidemiological analysis was used to explore the epidemiological characteristics , pathogen distribution, clinical symptoms and signs as well as prognosis of HFMD and herpangina surveillance cases from January to May,2016 in Fengtai District. Results Surveillance cases of HFMD emerged from January, increased in March and peaked in May. Surveillance cases of herpangina emerged from March, and evidently increased in April and May. Both the HFMD and herpangina cases were mainly kindergarten children(63.1% and 77.8%), and mainly from migrant population and commodity market(89.29 % and 100%). The main HFMD pathogen was CoxA16 (20.2%), followed by other enteroviruses (16.7%). In contrast, all of the herpangina pathogens were other enteroviruses(100%),among which CoxA10 accounted for 27.78%. The incidence rates of fever, sore throat, headache, vomiting in herpangina cases(91.67%,69.44%,8.33%,5.56%)were significantly higher than those in HFMD cases(50.00%,8.33%,0.00%,1.19%)(P<0.05). The 4-week follow up indicated that the incidence rate of peeling was significantly higher in HFMD cases(27.38 %) than in herpangina ones(0.00%)(P<0.05). Conclusions As enterovirus infectious diseases, herpangina and HFMD are quite similar in epidemiological characteristics. Some clinical symptoms are more evident in herpangina cases. Appropriate prevention and control measures should be introduced for herpangina, and it should be included into legal monitoring management.
2017, Vol. 24 
