Abstract：Objective To explore the risk factors of hand, foot and mouth disease (HFMD) among scattered migrant children in Shanghai City so as to provide scientific evidence for HFMD prevention and control. Methods One hundred and seventy scattered migrant children diagnosed with HFMD from June 2012 to May 2013 were selected as the case group, while 340 healthy scattered migrant children in the same community served as the control group. A case-control study was conducted to identify the risk factors of HFMD. Unified questionaires were used in this investigation, and EpiData 3.1 software was employed for setting up a database. SPSS19.0 software was applied to performing univariate and multivariate unconditional logistic regression analyses. Results Univariate logistic regression analysis showed that caregiver’s education level, family income, contacting with patients within 1 week, visit to densely populated places, finger-biting, toy-biting, young children’s frequency of hand washing, cleanliness of children’s hands, caregivers’ hand washing frequency were the factors influencing HFMD onset in the scattered migrant children. Multivariate conditional logistic regression analysis showed that contacting with HFMD cases within 1 week (OR=19.089, 95%CI:9.904-36.794, P=0.000) and finger-biting (OR=1.614, 95%CI:1.037-2.514, P=0.034) were the risk factors for HFMD in the scattered migrant children, while high family income (OR=0.632, 95%CI:0.440-0.908, P=0.013) and high frequency of caregivers’ hand washing (OR=0.691, 95%CI:0.494-0.966, P=0.030) were the protective factors. Conclusions There are many factors affecting HFMD incidence in the scattered migrant children in Shanghai City. Emphasis should be placed on implementing home quarantine after HFMD onset and educating children to develop good habits of hand hygiene, including no sucking fingers and washing hands before meals and after using toilets. Publicity campaign regarding promoting hand hygiene of parents and caregivers of the scattered migrant children is also crucial to preventing HFMD in this group.
李恩国， 徐兴兴， 周洲， 潘浩. 上海市外来散居儿童手足口病发病的危险因素研究[J]. 实用预防医学, 2017, 24(1): 57-60.
LI En-guo, XU Xing-xing, ZHOU Zhou, PAN Hao. Risk factors of hand, foot and mouth disease in the scatteredmigrant children in Shanghai City. , 2017, 24(1): 57-60.
[1] Krakauer T,Stiles BG.The Staphylococcocal enterotoxin family: SEB and siblings[J].Virulence,2013,4(8):759-773. [2] Scallan E, Hoekstra RM, Angulo FJ, et al. Foodborne illness acquired in the United States-major pathogens[J]. Emerg Infect Dis,2011,17(1):7-15. [3] 张红芝,朱召芹,陈海丽,等.金黄色葡萄球菌食品分离株肠毒素基因分布及分型研究[J].中国食品卫生杂志,2012,24(5):417-420. [4] 沈玄艺,宋启发,徐景野,等.食源性金黄色葡萄球菌肠毒素基因型分布研究[J].中国食品卫生杂志,2012,24(5):427-429. [5] 周藜,周倩,朱玫,等.贵州省食源性金黄色葡萄球菌肠毒素及耐药分析[J]. 中国卫生检验杂志,2014,24(22):3318-3320. [6] 卫沛楠,吕国平, 徐保红,等.食源性金黄色葡萄球菌9 种肠毒素基因的多重PCR检测[J].现代预防医学,2013,40(17):3269-3272. [7] Zouharova M,Rysanek D.Multiplex PCR and RPLA identification of Staphylococcus aureus enterotoxigenic strains from bulk tank milk[J].Zoonoses Public Health, 2008, 55(6):313-319. [8] Hattermann K,Held-Feindt J, Lucius R, et al. The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects[J]. Cancer Res,2010,70(8):3299-3308.
2017, Vol. 24 
