Abstract:Objective To analyze the epidemiological and etiological characteristics of rotavirus diarrhea in Shenzhen City from 2010 to 2015 so as to provide a basis for conducting scientific prevention and control and exploring the research direction. Methods Descriptive epidemiological method was used to analyze the information about the reported rotavirus diarrhea cases from China Information System for Disease Control and Prevention and the data regarding sentinel monitoring of pathogen spectrum of viral diarrhea in Shenzhen City during 2010-2015. Results Totally 113,823 cases of rotavirus diarrhea were reported in Shenzhen City from 2010 to 2015. The incidence rates in 2010, 2011, 2012, 2013 and 2015 were 150.17/100,000, 186.55/100,000, 147.08/100,000, 298.82/100,000, 146.76/100,000 and 149.76/100,000 respectively. The average incidence rate was 179.86/100,000, and the incidence peaked in 2013. Rotavirus outbreaks began to rise around October each year, with a peak occurring in November and December. Rotavirus outbreaks had obvious regional aggregation characteristics. Rotavirus diarrhea predominated in the suburbs, like Baoan District and Longhua District, where migrants congregated, but was not prevalent in downtown districts, like Nanshan District and Futian District, and Dapeng New Tourist District in Shenzhen east coast. Most cases were male patients (61.8%), and patients aged 2 years and below were in the majority (83.2%). The sentinel laboratory-based surveillance of pathogens showed that the monthly distribution trend of the positive rate of rotavirus was consistent with the epidemic trend. P[8] was the dominant genotype in VP4 serotype during 2011-2015. According to G/P type, G9P[8] was the main kind of rotavirus strain in 2011, G9P[8], G1P[8] and G3P[8] were the main kinds of rotavirus strains in 2012, G1P[8] was the main kind of rotavirus strain in 2013, and G9P[8] was again the main kind of rotavirus strain in 2014 and 2015. Conclusions The epidemics of rotavirus diarrhea in Shenzhen City during 2010-2015 were generally steady, but the changes of the predominant G type were related to the wide fluctuation of the epidemics. It is necessary to enhance rotavirus diarrhea prevention and control in floating population gathering districts and to pay more attention to surveillance on rotavirus genotype and exploration of immunization strategy.
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