Abstract：Objective To solve the problem of preventive vaccination of children with Kawasaki disease for grassroots doctors. Methods The experts in pediatrics, epidemiology and vaccinology were invited to demonstrate preventive vaccination strategy for children with Kawasaki disease and consensus recommendations were expected to reach. Notification before inoculation was conducted among the guardians of children who met the vaccination requirement, vaccination was performed after the informed consent form was signed, and post-vaccination safety was observed. Results Consensus recommendations regarding preventive vaccination of Kawasaki disease children without complications, with complications and with relapse were reached. 6 children were vaccinated under the guidance, and no adverse reactions were found. Conclusions Using proposed vaccination consensus recommendations derived from expert reasoning conference to guide the inoculation of Kawasaki disease children can improve the vaccination rate and ensure the safety of vaccination. The approach is safe and feasible.
黄蓉, 肖雷, 王凤双, 张松建, 孙美平. 多学科专家论证川崎病儿童预防接种模式应用[J]. 实用预防医学, 2018, 25(8): 1011-1014.
HUANG Rong, XIAO Lei, WANG Feng-shuang, ZHANG Song-jian, SUN Mei-ping. Application of multidisciplinary expert demonstration on preventivevaccination model of children with Kawasaki disease. , 2018, 25(8): 1011-1014.
[1] Burns JC.The riddle of Kawasaki disease[J].N Engl J Med,2007,356(7):659-661. [2] Park YW,Han JW,Hong YM,et al. Epidemiological features of Kawasaki disease in Korea,2006-2008 [J]. Pediatr Int,2010,53(1):36-39. [3] Huang WC,Huang LM,Chang IS,et al. Epidemiologic features of Kawasaki disease in Taiwan,2003-2006 [J]. Pediatrics,2009,123(3):e401-405. [4] Lin YT,Manlhiot C,Ching JC,et al. Repeated systematic surveillance of Kawasaki disease in Ontario from 1995 to 2006 [J]. PediatriInt,2010,52(5):699-706. [5] Singh S,Aulakh R. Kawasaki disease and Henoch Schonlein purpura:changing trends at a tertiary care hospital in north India (1993- 2008)[J]. Rheumatol Int,2009,30(6):771-774. [6] 王卫平,毛萌,李廷玉,等.儿科学[M].第8版.北京:人民卫生出版社,2013:192-194. [7] 杨波,朱义杰,罗军,等.川崎病流行病学、病因和发病机制的新进展[J].临床儿科杂志,2014,32(2):189-192. [8] 丁艳,尹薇,熊越华,等.川崎病患儿免疫功能的检测及临床价值[J].中华风湿病学杂志,2012,16(9):588-592. [9] 李晓惠.川崎病诊断与治疗新进展[J].中华实用儿科临床杂志,2013,28(1):9-13. [10] 刁连东,孙晓冬.实用疫苗学[M].上海:上海科学技术出版社,2015:103-105. [11] 上海市医学会儿科专业委员会免疫学组.免疫异常儿童疫苗接种(上海)专家共识[J].临床儿科杂志,2014,32(12):1181-1190. [12] Newburger JW, Takahashi M, Gerber MA, et al. Diagnosis, treatment, and long - term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever,Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association[J]. Pediatrics,2004,114(16):1708-1733. [13] Miura M, Katada Y, Ishihara J. Time interval of measles vaccination in patients with Kawasaki disease treated with additional intravenous immune globulin[J]. Eur J Pediatr,2004,163(1):25-29.
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