Abstract：Objective To establish a rapid and simple method for the determination of mercury in urine, which can meet the requirements of national standard of biological monitoring. Method A direct mercury analyzer was used to investigate and test the determination of mercury in urine. Results There was a good linear relationship between the peak area and mercury concentration when the mercury concentration in urine ranged between 1.6 μg/L and 100 μg/L, and the correlation coefficient was above 0.999. The detection limit and quantitative limit of the method were 0.5 μg/L and 1.6 μg/L respectively. The inter-batch and intra-batch relative standard deviations (RSDs) were both less than 5%. Spiking three concentration levels of mercury (including 10μg/L, 30μg/L and 60μg/L) in urine samples, the recoveries of standard addition were 91.6%-99.9%. The results were consistent with reference material certificates and cold atomic absorption method result. Conclusions This direct mercury analyzer method, as a simple and rapid method for the determination of mercury, can meet the requirements of detection method of chemical substance in biomaterial; and hence, it can be used for the determination of mercury in urine of occupational exposure.
尹江伟,刘祖强,闫慧芳,朱志良. 直接测汞仪法测定尿中汞国标方法的研制[J]. 实用预防医学, 2018, 25(4): 505-507.
YIN Jiang-wei, LIU Zu-qiang, YAN Hui-fang, ZHU Zhi-liang. National standard method of determining mercury in urine by a direct mercury analyzer. , 2018, 25(4): 505-507.
2018, Vol. 25 
