Abstract：Objective To preliminarily investigate the infection status of influenza virus in main hosts in Chengdu City so as to provide a scientific basis for influenza prevention and control. Methods Fifty check-up persons from the Physical Examination Department of Chengdu Municipal Center for Disease Control and Prevention and 49 swines from the slaughterhouse of urban area in Chengdu in 2014 were investigated. Serum samples were collected and haemagglutination inhibition (HI) assay with representative strains (A (H1N1), H3N2, B-Victoria and B-Yamagata) isolated in the same period as antigens were carried out to detect the corresponding antibodies. Combined with the local epidemic situation of influenza, the infection status in and between the hosts were analyzed. Results The positive detection rates of subtypes of influenza viruses in the influenza-like cases were statistically significant (χ2=50.393, P<0.001), with the highest positive rate (6.03%) for influenza B-Yamagata lineage virus. As for human serum samples, HI antibody positive rates of influenza B-Yamagata and B-Victoria lineage virus strains were higher than those of the other influenza viruses (χ2=239.104, P<0.001), while the positive rates of influenza A (H1N1) and B-Yamagata lineage virus strain in swine serum samples were higher than those of the other influenza viruses (χ2=231.642, P<0.001). Generally, the antibody titers of A (H1N1), H3N2, B-Victoria and B-Yamagata were statistically higher in human serum samples than in swine serum samples (χ2=17.099, P=0.008; χ2=31.581, P<0.001; χ2=57.623, P<0.001; χ2=5.713, P=0.032). Conclusions The check-up persons from the Physical Examination Department of Chengdu Municipal Center for Disease Control and Prevention in 2014 get higher infection rates of influenza A(H1N1) and B virus and the infection of B-Yamagata in crowd fails to form an effective immune barrier to prevent pathogen cycling. Swine may be a potential host of human influenza B virus.
孟建彤， 陈振华，任红兵，黄韦唯，白艳，黄薇，张晓春. 2014年成都市人和猪体内人流感病毒感染状况初步调查[J]. 实用预防医学, 2017, 24(11): 1308-1310.
MENG Jian-tong, CHEN Zhen-hua, REN Hong-bing, HUANG Wei-wei, BAI Yan, HAUNG Wei, ZHANG Xiao-chun. Preliminary investigation on infection status of seasonal influenza virus in human and swine in Chengdu City, 2014. , 2017, 24(11): 1308-1310.
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