Abstract：Objective: To study the children with mycoplasma pneumoniae pneumonia (MPP) in bronchoalveolar lavage fluid (BALF) T cell subsets in the distribution of the MPP of immune injury mechanism, provide experimental basis for the possibility of MPP immunological therapy;Methods: collected in January 1, 2012 - December 31, 2012, pediatrics medical centre of Hunan provincial people's hospital in 78 cases with children with MPP were treated respectively in the acute phase and convalescence BALF collected samples via fiberoptic bronchoscopy, take to collect in the same period because of bronchial foreign body, bronchial malformations and chronic cough in children hospital pediatric medical center BALF samples of 61 cases with flow cytometry technique to detect T lymphocyte subsets in the BALF; Results: MPP in patients with acute phase and convalescence CD3 + T cells compared with control group no significant difference (P > 0.05), and testing results of CD4 + and CD4 + / CD8 + MPP acute stage and MPP recovery are lower than the control group (P < 0.01), and CD8 + test results MPP acute phase and convalescence is higher than the control group (P < 0.01); Conclusion: cellular immune imbalance in the MPP children, this study further in the treatment of clinical application of immune modulators MPP provides a theoretical basis.
2014, Vol. 21 
