Abstract：Objective To understand the epidemiological characteristics and the antibody levels of rubella of gestational age women in Luohu of Shenzhen , to provide a scientific basis for reducing incidence of rubella,preventing CRS and improving the rubella immunization strategy．Methods The gestational age women aged 18-35 years in Luohu district of Shenzhen from 4 clinics for physic examination were selected, 164 blood samples were used to detect the IgG antibody level of rubella by using ELISA method．Meanwhile, the epidemiological characteristics of rubella for gestational age women during 2010-2013 were analyzed, Results.The antibody geometric mean concentration of rubella were 103.1626 IU/Ml,The antibody positive rate of rubella were 93.3%. The antibody concentration of rubella increased with age, but there is no difference between different age group ( x2 =2.7668,P =0．2507,F=1.00,P=0.905). the incidence rate of rubella was75%、75.63%、75% and 64.7%;there is no difference of the antibody positive rate of rubella between gestational age women in the city and outside city ( χ2 = 0．0238,P =0．8774),there is difference of the antibody geometric mean concentration of rubella between gestational age women in the city and outside city (F=0.207,P=0.991);Meanwhile, there is no difference of the antibody positive rate of rubella in gestational age women with clear or unknown immunization history and without vaccination history ( χ2 = 2．0691, P =0．3554,F=1.508,P=0.224). during 2010-2013 respectively. The highest morbidity of rubella was in 15-35 age group ,containing 74.84% of total gestational age women Conclusions It is suggests that the gestational age women should have the vaccination of rubella vaccine before pregnancy, increasing the antibody concentration to prevent CRS and infection in low age phage,
2014, Vol. 21 
