摘要 目的 调查分析郴州地区40岁以上人群中膝关节骨性关节炎患病率、分布情况以及发病危险因素,为临床治疗与预防提供理论依据。 方法通过整群随机抽样、入户问卷调查、体格检查、X 线拍片等方法调查郴州市区3个街道社区共300人,郴州周边1个自然村中3个组共300人。 结果郴州地区40岁以上人群中膝关节骨性关节炎患病率为19.2%严格来说,这仅是被调查的郴州地区40岁以上人群中膝关节骨性关节炎的检出率,患病率有些勉强。,其中男性(9.5%)低于女性(26.6%,P=0.000)全文如此格式修改,乡村(18.3%)与城区(20.0%,P>0.05)无统计学差异;有家族史的人群患病率明显升高(OR=4.267),女性较男性更容易患病(OR=3.968),随着年龄地增加,患病率逐渐升高(OR=2.351),随着BMI(Body Mass Index 体质指数)值升高患病率也逐渐升高(OR=1.423),坐姿较多的人群不易患病(OR=0.666)。 结论女性膝骨性关节炎患病率普遍高于男性,城乡间患病率无明显差别,性别差异、年龄、家族史和BMI值是KOA患病的危险因素,而职业习惯中的坐姿多为其保护因素。
Abstract：Objective This study is to evaluate the prevalence, distribution and risk factors of osteoarthritis of the knee in elderly population age>or=40 in Chenzhou City, Hunan Province, China, and provide theory evidence for clinical treatment and prevention. Methods Equal number of respondents were investigated in 3 urban communities and 3 rural groups through cluster random sampling, questionnaire survey and physical examination,and the total number was 600. The incidence of symptomatic osteoarthritis of the knee was estimated which combined with age, gender, family history, menopause, and district. Then the risk factors were analyzed by logistic regression analysis. Results The total prevalence of symptomatic osteoarthritis of the knee was 19.2%.The prevalence of osteoarthritis of the knee was 9.5% and 26.6% for men and women (P=0.000<0.05), 18.3% and 20.0% for rural and urban area (P>0.05), respectively. The prevalence of who had family history was highlighted (OR=4.267). Female has a higher risk of suffering from osteoarthritis of the knee than male(OR=3.968).The rise of the prevalence accompanied with rising age (OR=2.351) and BMI (OR=1.423).People who used to have setting posture has a lower risk of suffering from it(OR=0.666). Conclusion The prevalence of symptomatic osteoarthritis of the knee in women is generally higher than men. But there is no significant difference in urban and rural area. Gender,age, family history and BMI are the risk factors for osteoarthritis of the knee.The setting posture is protective factor.
曾敏川,李康华. 湖南省郴州地区膝关节骨性关节炎流行病学调查[J]. 实用预防医学, 2014, 21(10): 1157-1160.
Zeng Min-chuan, LI Kang-hua. Epidemiological investigation of osteoarthritis of the knee in Chenzhou City, Hunan Province. , 2014, 21(10): 1157-1160.
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