Abstract:Objective The aim of the study was to analyze the epidemiological features of AIDS death cases during antiviral therapy in Wenzhou City, so as to reduce the fatality rate of the sufferers and provide references for improving the therapeutic effects of AIDS antiviral treatment. Methods Data were collected from the National AIDS Comprehensive Prevention and Treatment System- the Management of Antivirus Treatment Database, and were analyzed by Excel and SPSS 17.0. Resutls A total of 94 AIDS patients died during antiviral therapy. 86.2% of them were males and 13.8% were females. Their average age was (55.55±15.27)years. The treatment fatality rate was 7.2%. For the groups with CD4+T cells ≤50/μl, 51-200 /μl and >200/μl , the fatality rates were 18.0%, 7.5% and 2.6% respectively. Most of the patients (59.6%) died of AIDS related diseases. Patients who died within 3 months of treatment accounted for 54.2%, and those died within 12 months accounted for 70.2%. Conclusion s AIDS patients’ death during antiviral therapy in Wenzhou City
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苏德华, 王大勇, 叶振淼, 赵丽娜, 金茜, 汪若秋, 陈向阳. 温州市艾滋病抗病毒治疗死亡病例流行病学分析[J]. 实用预防医学, 2015, 22(5): 556-558.
SU De-hua, WANG Da-yong, YE Zhen-miao, ZHAO Li-na, JIN Qian, WANG Ruo-qiu, CHEN Xiang-yang. Epidemiological analysis of AIDS death cases during antiviral therapy in Wenzhou City. , 2015, 22(5): 556-558.
[1] 王陇德.艾滋病学[M].北京:北京出版社.2009. [2] Yang X, Li QR, Sun L,etal.The effect of highly active antiretroviral therapy on immune function in HIV/AIDS patients.[J] The Chinese Journal of Dermatovenereology,2008,22(3):36-37 杨璇,李倩如,孙蕾,等.高效抗逆转录病毒疗法(HAART)对HIV/AIDS患者免疫功能的影响[J].中国皮肤性病学杂志,2008,22(3):36-37. [3] Su DH,Wang DY,Zhao LN,etal. Analysis on characteristics of AIDS patients before receiving national free antiretroviral treatment in Wenzhou,2005 – 2013[J]Disease surveillance,2014,29(6):469-2-472 苏德华、王大勇、赵丽娜,等,2005-2013年浙江省温州市艾滋病免费抗病毒治疗患者流行病学特征分析[J]疾病监测,2014,29(6):469-472 [4] Ou QY ,Wei XQ ,Chen X,et al. Analysis of Death Relative -factors of AIDS Patients After Free Antiretroviral Treatment in Hunan Province[J] Practical Prevent ive Medicine, 2007,14(3):672-673 欧秋英, 魏秀青, 陈曦,等,湖南省艾滋病抗病毒治疗死亡患者相关因素分析[J]实用预防医学,2007,14(3):672-673 [5] Li QH,Gao YQ,Sun X,etal. Clinical study of highly active anti-virus treatment of HIV/AIDS patient. [J]The Chinese Journal of Dermatovenereology ,2009,23(12):799-801. 李群辉,高艳青,孙欣,等,高效抗逆转录病毒疗法治疗HIV/AIDS患者的临床研究[J].中国皮肤性病学,2009,23(12):799-801. [6] Fu XB, Ling P, Liu YY,etal. Analysis of factors affecting the survival time after AIDS antiretroviral therapy in Guangdong Province [J]South China Journal of Preventive Medicine,2009,35(3):1-4. 付笑冰,林鹏,刘勇鹰,等.广东省艾滋病患者抗病毒治疗后生存时间分析[J].华南预防医学,2009,35(3):1-4. [7] Yu SQ,Song MM,Peng RS,Liu DY . Analysis of the outcomes of antiviral therapy to treat adults with HIV/AIDS from 2006 to2012 in Weifang Shandong Province[J] Journal of Pathogen Biology,2013,8(3):260—262( in Chinese) 于绍起,宋明明,,彭仁生,刘冬莹,2006~2012年潍坊市成人艾滋病抗病毒治疗转归分析[J],中国病原生物学杂志,2013,8(3):260—262 [8] 谢年华,孙敏,王夏,等.武汉市艾滋病病人终止抗病毒治疗原历分析[J].中国艾滋病性病,2010,16(5):510 [9] Lai WH , Yu H , Zhou S, etal. An analysis of factors related to survival of AIDS patients receiving highly active antiretroviral therapy in Sichuan province[J]Chinese Journal of AIDS &STD, 2011,17( 3) : 298-301. 赖文红,喻航,周顺,等. 四川省艾滋病抗病毒治疗病人生存时间影响因素分析[J]. 中国艾滋病性病,2011,17( 3) : 298-301.