Prevalence rate of hyperuricemia and its related factors among residents aged 30-79 years in Chongqing Municipality
DING Xianbin1, CHEN Liling1, TANG Wenge1, CHEN Ting1, XU Jie1, LYU Xiaoyan1, MAO Deqiang1, TANG Cheng2, LONG Feng3
1. Institute of Non-communicable Disease Prevention and Control, Chongqing Center for Disease Control and Prevention, Chongqing 400042, China; 2. Jiulongpo District Center for Disease Control and Prevention, Chongqing 400051, China; 3. Tongnan District Center for Disease Control and Prevention, Chongqing 402660, China
Abstract:Objective To analyze the prevalence rate of hyperuricemia and its related influencing factors among residents aged 30-79 years in Chongqing Municipality, and to provide a basis for performing prevention and control of hyperuricemia. Methods The subjects surveyed were recruited from the Han permanent residents aged 30-79 years in 13 districts or counties in Chongqing Municipality. A questionnaire survey, physical examinations and laboratory tests were performed among the subjects by using a stratified sampling method. Chi-square test was employed to compare the prevalence rates of hyperuricemia in populations with different features. The related factors affecting hyperuricemia were analyzed by multivariate logistic regression analysis. Results A total of 22,449 residents were surveyed in this study, including 10,512 (46.83%) males and 11,937 (53.17%) females. The detection rate of hyperuricemia was 10.76% (95%CI:9.40%-12.12%), and the prevalence rate of hyperuricemia was higher in males (20.27%, 95%CI:15.25%-25.29%) than in females (2.38%, 95%CI:0.95%-3.81%) (P<0.05). The results of multivariate logistic regression analysis revealed that males (OR=24.621, 95%CI:9.947-60.947), young population (aged 30-39 years) (OR=2.327, 95%CI:1.471-3.681), high socioeconomic status (OR=1.537, 95%CI:1.174-2.012), non-smoking (OR=1.430, 95%CI:1.153-1.773), having a history of harmful alcohol use (OR=1.458, 95%CI:1.127-1.887), central obesity (OR=2.285, 95%CI:1.885-2.771), hyperlipidemia (OR=2.440, 95%CI:2.009-2.964), hypertension (OR=1.509, 95%CI:1.236-1.843) and normal glucose (OR=1.677, 95%CI:1.257-2.237) were risk factors for hyperuricemia. Conclusion The prevalence rate of hyperuricemia among the residents in Chongqing Municipality was low. Special attention should be paid to interventions targeting males, young population, residents with high socioeconomic status or harmful alcohol use, obese population and patients with hyperlipidemia or hypertension so as to reduce the risk of hyperuricemia.