Epidemiological survey on the first dead case of COVID-19 in Hunan Province
CAI Liang, DUAN Hong-bo, ZHANG Zhao-qiang, LIU Shu-jun, GAO Li-dong
Hunan Provincial Center for Disease Control and Prevention/Hunan Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of Medical Sciences, Changsha, Hunan 410005, China
Abstract：Objective To analyze the source of infection and cause of death in the first dead case of COVID-19 in Hunan Province. Methods According to the requirements of National Novel Coronavirus Pneumonia Prevention and Control Scheme (the 3rd Edition), field epidemiological methods were used to trace the source of infection and collect the nasopharyngeal swabs of the patient and the suspected infection source to detect the 2019-nCoV viral nucleic acid by real-time RT-PCR. All of the close contacts were isolated at the assembly sites for medical observation. The epidemiological and clinical diagnosis and treatment data of the case were analyzed. Results On January 21, 2020, the patient had a transient contact with a COVID-19 case having a history of travelling in Wuhan, and developed chill and fever on January 26. The patient was diagnosed as a confirmed COVID-19 case on February 4. The patient suffered from anemia, hypertension and renal insufficiency, and had a history of right kidney atrophy and a surgical history of ureter implantation 19 days before onset. The patient had a history of diarrhea during the whole course of the disease, and died on February 8, regarding as the first dead case of COVID-19 in Hunan Province. Conclusion The first dead case of COVID-19 in Hunan Province had a high correlation with the COVID-19 patient with a history of travelling in Wuhan. Suffering from underlying diseases was the important cause of death in the first dead case.
蔡亮, 段宏波, 张兆强, 刘树俊, 高立冬. 湖南省首例新型冠状病毒肺炎死亡病例流行病学调查分析[J]. 实用预防医学, 2021, 28(8): 926-929.
CAI Liang, DUAN Hong-bo, ZHANG Zhao-qiang, LIU Shu-jun, GAO Li-dong. Epidemiological survey on the first dead case of COVID-19 in Hunan Province. , 2021, 28(8): 926-929.
[1] Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster[J]. Lancet, 2020,395(10223):514-523. [2] Li X,Wang W,Zhao X,et al. Transmission dynamics and evolutionary history of 2019-nCoV[J]. J Med Virol, 2020,92(5):501-511. [3] Lu R,Zhao X,Li J,et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding[J]. Lancet, 2020, 395(10224):565-574. [4] 中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组.新型冠状病毒肺炎流行病学特征分析[J].中华流行病学杂志,2020,41(2):145-151. [5] Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia[J]. N Engl J Med, 2020,382(13):1199-1207. [6] 中华预防医学会新型冠状病毒肺炎防控专家组.新型冠状病毒肺炎流行病学特征的最新认识[J].中华流行病学杂志,2020,41(2):139-144. [7] 刘子言,高立冬,胡世雄,等.湖南省697例新型冠状病毒肺炎确诊病例就诊及诊断分析[J].实用预防医学,2020,27(5):513-516. [8] Guan WJ, Ni ZY, Hu Y, et al. China Medical Treatment Expert Group for COVID-19. Clinical characteristics of coronavirus disease 2019 in China[J]. N Engl J Med, 2020,382(18):1708-1720. [9] 钟慧钰,赵珍珍,宋兴勃,等. 新型冠状病毒核酸临床检测要点及经验[J]. 国际检验医学杂志,2020,41(5):523-526.
2021, Vol. 28 
