Abstract：Objective To investigate the reported incidence of hepatitis B and the current status of its serum immunization in recent years in Songjiang District of Shanghai, to evaluate the effectiveness of hepatitis B control so as to provide a basis for further adopting measures.MethodsDescriptive epidemiological method was used to analyze the reported incidence of hepatitis B in Songjiang District of Shanghai from 2006 to 2015. Seroepidemiological data from a national seroepidemiological survey of hepatitis B in the survey site of Songjiang District in 2014 were used to analyze the infection status of hepatitis B virus.Results A total of 6,339 cases of hepatitis B were accumulatively reported in Songjiang District from 2006 to 2015. The incidence rate was 54.14/100,000, and showed a declined tendency (χ2trend=296.850, P=0.000). The incidence rate of acute hepatitis B was significantly lower than that of chronic hepatitis B (7.35/100,000 vs. 45.09/100,000, χ2=3,179.779, P=0.000), and both the incidence rates showed a declined tendency (χ2trend=487.127, P=0.000; χ2trend=42.415, P=0.000). The reported incidence rate of hepatitis B was the highest in the age group of 35- years. The incidence rate before 40 years old increased with the increment of age (χ2trend=1,388.621, P=0.000), while that after 40 years old decreased with the increment of age (χ2trend=493.030, P=0.000). The high-risk age of hepatitis B infection was 20-54 years old. The incidence rate of males (77.79/100,000) was higher than that of females (28.95/100,000), of which the incidence rates of males with acute hepatitis B, chronic hepatitis B and undifferentiated hepatitis B were all higher than those of females (all P<0.01). The positive rates of HBsAgandanti-HBsin resident population aged 1-29 years during the national seroepidemiological survey was 0.47% and 58.60% respectively. 182 participantswere confirmed to receive hepatitis B vaccine, and the vaccination rate was 84.65%, of which the vaccination rate of children aged less than 15 years was 100.00%. No statistically significant differences were found in the positive rate of HBV immunological marker and use of HBV vaccine between the two genders (both P>0.05). HBsAg seropositivity was not detected among children aged below 15 years. The anti-HBs positive rate of the age group of 1- year was higher than those of the age groups of 5- years (χ2=17.038, P=0.000) and 15-29 years (χ2=5.502, P=0.019), but no statistically significant difference was found in the anti-HBs positive rate between the age groups of 5- years and 15-29 years (χ2=2.835, P=0.092). The anti-HBc positive rate increased with the increment of age (P<0.05).ConclusionsGood results are achieved in the prevention and control of hepatitis B in Songjiang District of Shanghai in 2006-2015, especially among people received hepatitis B vaccine in the National Immunization Program.
张清慧, 李萌, 孔园园, 黄锐. 2006-2015年上海市松江区乙型病毒性肝炎流行状况及防控效果评价[J]. 实用预防医学, 2017, 24(6): 716-719.
ZHANG Qing-hui, LI Meng, KONG Yuan-yuan, HUANG Rui. Prevalence of hepatitis B and evaluation on the effectiveness of its prevention andcontrol in Songjiang District of Shanghai, 2006-2015. , 2017, 24(6): 716-719.
2017, Vol. 24 
