Abstract：ObjectiveTo analyze the epidemiological characteristics and regularity of human avian influenza A (H7N9) and provide the scientific evidence for the prevention and control of disease. MethodsEpidemiological analysis was conducted on 25 laboratory confirmed cases of human infection with H7N9 virus in Shenzhen．ResultsThe 25 cases were confirmed during December 19,2013 - may 1, 2014．Of the 2 deaths, 14 cases were males. 11 cases were females. The youngest of six years old, The oldest of 81 years old. The median of patients’age was 53 years old．17 cases are 40 years or older, with the proportion of 68.0%. Epidemiological survey indicated that of the 16 cases had histories of exposure to alive poultry markets．Medical supervision was conducted for 867 close contacts|including 631 medical staff．No secondary cases were found．Conclusion old people are the susceptible population of human avian influenza A ( H7N9) ．and no evidence of human to human transmission was found．Standard management of alive poultry markets is important to prevent H7N9 virus infection in urban population|and it is necessary to expand and strengthen the surveillance of Fever pneumonia and Unexplained pneumonia and control the spread of H7N9 virus．
[1] Gao R, Cao B, Hu Y,et al. Human infection with a novel avian-origin influenza A(H7N9)virus[J]. N Engl J Med,2013,368(20):1888-1897. [2] Parry J, H7N9 avian flu infects humans for the first time. BMJ, 2013,346:f2151. [3] 闫铁成,肖丹,王波,等.中国大陆130例人感染H7N9 禽流感病例流行病学特征分析[J].中华疾病控制杂志,2013,17(8):651-654. [4] 刘社兰,柴程良,等,中国人感染H7N9禽流感流行现状与防控对策[J].中华临床感染病杂志,2013,6（3）：132-135. [5] Hancock K,Veguilla V,Lu XH,et al．Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus[J]．N Engl J Med,2009,361( 20):1945-1952． [6] Centers for Disease Control and Prevention(CDC)．Serum cross reactive antibody response to a novel influenza A ( H1N1) virus after vaccination with seasonal influenza vaccine [J]． MMWR Morb Mortal Wkly Rep,2009,58( 19) : 521-524． [7] 周莉芸,高魏,等,2例人感染H7N9 禽流感轻症病例的流调报告及分析[J].实用预防医学杂志,2013,（20）5：571-572. [8] Chen Y,Liang W, Yang S,et al. Human infections with the emerging avian influenza A H7N9 viral from wet market poultry; clinical analysis and characterization of viral genome. Lancet,2013,381:1916-1925. [9] Liu D,Shi W,Shi Y,etal．Origin and diversity of novel avian Influenza AH7N9 viruses causing human infection：phylogenetic,structural,and coalescent analyses[J]．Lancet,2013,381（9881）：1926–1932． [10] 修文琼,等,新型H7N9禽流感病毒研究进展[J]. 中国人兽共患病学报,2014,30（6）：636-644. [11] Li Q, Zhou L, Zhou M, et al, preliminary report: epidemiology of the avian influenza A (H7N9) outbreak in china[J]．N Engl J Med,2013, [Epub ahead of print] [12] Bao CJ,Cui LB,Zhou MH,et al, Live-Animal Markets and Influenza A (H7N9) Virus Infection[J].N Engl J Med,2013,368(24): 2337-2339.
2015, Vol. 22 
