Abstract：ObjectiveTo establish a method for enrichment and determination of trace bisphenol A (BPA) in water samples by ultrasound assisted dispersive liquid - liquid microextraction (DLLME) combined with high performance liquid chromatography (HPLC). MethodsExperimental conditions of chromatographic separation and DLLME such as type and volume of extractants and disperser solvents, ultrasonic microextraction time and extraction time were investigated. Enrichment factor (EF) was employed to evaluate the extraction efficiency. ResultsUnder the optimized conditions, the chromatographic peak areas were proportional to the concentrations of BPA in the range of 0.0002 - 0.2mg/L, with correlation coefficient more than 0.9994, the limit of detection was 0.01μg/L. The method was applied in the enrichment and determination of BPA in the real water samples with the average recoveries of 88.7% - 101.0%, and the relative standard deviations of 4.4% - 7.5%. ConclusionsThe developed procedure is suitable for the enrichment and determination of trace BPA in different real water samples.
马淑青, 王丹, 管益涛. 高效液相色谱法测定水样中痕量双酚A[J]. 实用预防医学, 2015, 22(10): 1177-1179.
MA Shu-qing, WANG Dan, Guan Yi-tao. Determination of Trace Bisphenol A in Water Samples by High Performance Liquid Chromatography. , 2015, 22(10): 1177-1179.
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