Abstract：ObjectiveTo understand the adherence to antiretroviral therapy (ART) among AIDS patients in Nanhai District, Foshan City and explore its influencing factors. MethodsTotally, 200 cases of AIDS patients were randomly selected from Nanhai District, Foshan City based on the AIDS prevention and control information management system. Their medication adherence, reasons for not-taking or missing taking medicine and adverse reactions were investigated with questionnaire. Their medication adherence was assessed in accordance with Morisky’s standard. The influencing factors were analyzed by Chi-square test and multivariate logistic regression analysis.ResultsIn 180 patients, 88 patients had medication compliance, with a compliance rate of 48.9%. Their medication time varied from 1 month to 6 years. 147 cases (81.7%) received the medication scheme of AZT+DDI+NVP or D4T+DDI+NVP combination. The top three drug adverse reactions were headache and dizziness(27.5%), gastrointestinal reactions like nausea, vomiting and diarrhea (20%), as well as drug rash and pruritus(16.2%). Multivariate logistic regression analysis showed that education background and medication time were the main factors affecting the adherence to highly active anti-retroviral therapy（HAART）among AIDS patients. ConclusionsThe medication adherence to HAART in AIDS patients in Nanhai District, Foshan City is low. Education background and medication time are the main influencing factors.
李景锋,周建平,黄喜明,潘宇韵,朱小朴. 佛山市南海区艾滋病患者抗病毒治疗服药依从性及影响因素研究[J]. 实用预防医学, 2015, 22(4): 432-435.
LI Jing-feng, ZHOU Jian-ping, HUANG Xi-ming, PAN Yu-yun, ZHU Xiao-pu. Study on adherence to antiretroviral therapy and its influencing factors among AIDS patients in Nanhai District, Foshan City. , 2015, 22(4): 432-435.
[1] 李东民，汪宁. 艾滋病自然史研究进展[J]. 中华流行病学杂志，2009，30（7）：743-746 [2] 曾刚，吴尊友. 医疗机构主动提供艾滋病检测咨询策略的卫生经济学评价研究进展[J]. 中华流行病学杂志，2012，33（1）：115-118. [3] 蒙琪琳. 艾滋病病人依从性的研究进展[J]. 中国农村卫生，2014，2（2）：523-524. [4] aagilign S, Deribew A, Amberbir A, et a1. Barriers and facilitators to antiretroviral medication adherence among HIV-infected paediatric patients in Ethiopia: a qualitative study [J]. SAHARA J, 2009, 6(4): 148-154. [5] 杨桂荪，梁炽强，文红娟，等. 佛山市禅城区艾滋病患者抗病毒治疗服药依从性分析[J]. 中国健康教育，2013，29（5）：447-449 [6] Oku AO, Owoaje ET, Oku OO, et a1. Prevalence and determinants of adherence to highly active antiretroviral therapy amongst people living with HIV/AIDS in a rural setting in south-south Nigeria [J]. Afr J Reprod Health, 2014, 18(1): 133-143. [7] Pefura-Yone EW, Soh E, Kengne AP, et a1. Non-adherence to antiretroviral therapy in Yaounde: prevalence, determinants and the concordance of two screening criteria [J]. J Infect Public Health, 2013, 6(4): 307-315. [8] Elliott J, Phlong P, Saphon V, et a1. Social meanings of adherence to antiretroviral therapy in Cambodia [J]. Cult Health Sex, 2011, 13(6): 685-697. [9] Cicconi P, Cozzi-Lepri A, Castagna A, et a1. Insights into reasons for discontinuation according to year of starting first regimen of highly active antiretroviral therapy in a cohort of antiretroviral-na?ve patients [J]. HIV Med, 2010, 11(2): 104-1113. [10] Beyene KA, Gedif T, Gebre-Mariam T, et a1. Highly active antiretroviral therapy adherence and its determinants in selected hospitals from south and central Ethiopia [J]. Pharmacoepidemiol Drug Saf, 2009, 18(11): 1007-1015. [11] 舒彬，牛姬飞，张胜男，等. 深圳市福田区艾滋病患者抗病毒治疗相关情况分析[J]. 实用预防医学，2014，21（1）：39-40，46. [12] 张传芳，张贻瑞，范江静，等. 湖南省TB/HIV双感患者治疗依从性调查及影响因素分析[J]. 实用预防医学，2013，20（12）：1439-1441
2015, Vol. 22 
