Abstract：Objective To explore the relationship between prognostic nutritional index (PNI) and the risk of depression in stroke patients so as to provide references for prognostic management of patients with stroke. Methods Stroke survivors selected from the National Health and Nutrition Examination Survey (NHANES) database from 2017 to 2020 served as the research subjects. Their depression status was assessed, and PNI was calculated. Multivariate logistic regression was used to analyze the effect of PNI on the risk of depression in the stroke patients. Results A total of 443 subjects were enrolled into this survey, including 220 males and 223 females, with the average age of (65.22±12.44) years. A total of 95 (21.44%) cases of depression were detected. The PNI score was lower in post-stroke depression patients than in non-depressed patients ((47.23±7.01) vs. (49.59±5.51)), showing a statistically significant difference between the two groups (P<0.05). The results of multivariate logistic regression displayed that after adjusting for confounding factors such as gender, age, education level, marital status and smoking history, the increase of PNI score had a significantly protective effect on post-stroke depression (OR=0.929, 95%CI:0.892-0.968, P<0.05). Conclusion The increase of PNI score has a certain effect on reducing the risk of depression in the stroke patients. It is of great significance for preventing depression and improving prognosis in the stroke patients to maintain better nutritional status and immune function.
崔明鹏, 崔翔宇, 鲁国, 王宝娟, 杨莹莹. 预后营养指数对脑卒中后抑郁风险的影响:基于NHANES 2017—2020年的横断面调查[J]. 实用预防医学, 2024, 31(4): 407-410.
CUI Mingpeng, CUI Xiangyu, LU Guo, WANG Baojuan, YANG Yingying. Effect of prognostic nutritional index on the risk of depression in stroke patients: a cross-sectional survey based on NHANES, 2017-2020. , 2024, 31(4): 407-410.
2024, Vol. 31 
