Abstract：Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) infection. After Mtb infects humans, its infection status is closely related to the host's own immunity, metabolism, and genetic mechanisms. Gut microbiota and its metabolites play important roles in the pathophysiological process and treatment of tuberculosis by participating in the host's immune response and metabolism. This article reviews the “lung-gut axis”, the role of gut microbiota-generated metabolites in Mtb infection, the impact of tuberculosis chemotherapy on gut microbiota, and the potential role of gut microbiota in tuberculosis treatment.
易一行, 喻容, 谢锦慧, 周婷, 向延根. 肠道菌群在结核分枝杆菌感染及其治疗中的相关性研究进展[J]. 实用预防医学, 2021, 28(12): 1546-1549.
YI Yi-hang, YU Rong, XIE Jin-hui, ZHOU Ting, XIANG Yan-gen. Research progress on the correlation of gut microbiota with Mycobacterium tuberculosis infection and its treatment. , 2021, 28(12): 1546-1549.
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