Abstract：Objective To explore the effect of contraceptive use before pregnancy on the days of pregnancy. Methods Propensity score matching method was used in this study, with the basic data as matching conditions. Contraceptive users were treated as the observation group and non-contraceptive users serving as the control group were matched according to 1∶4. Data regarding the days of pregnancy were obtained by follow-up visits, and then the relationship between contraceptive use before pregnancy and the days of pregnancy was explored. Results A total of 241 cases were matched in the contraceptive group and 964 cases in the control group. There was no significant difference in the data after matching (P>0.05). Cox regression analysis showed that the use of contraceptives could shorten the days of pregnancy after adjusting the basic data, with the hazard ratio (HR) of 0.85 (95%CI:0.74-0.98). Subgroup analysis displayed that taking contraceptives before pregnancy could shorten the days of pregnancy in the three subgroups at the age ≥31 years, with body mass index ≥24 and without history of pregnancy, with the HRs (95%CI) of 0.76 (0.59, 0.97), 0.67 (0.46, 0.98) and 0.78 (0.63, 0.96), respectively. Conclusion Taking contraceptives before pregnancy may shorten the days of pregnancy, especially in women with advanced age, obesity and at first pregnancy; and hence, more attention should be paid to contraceptive use among them.
庾静云, 甘展鹏, 姜碧, 曾思良. 基于倾向性评分匹配方法的孕前使用避孕药和妊娠天数的相关性分析[J]. 实用预防医学, 2021, 28(6): 658-660.
YU Jing-yun, GAN Zhan-peng, JIANG Bi, ZENG Si-liang. Correlation between contraceptive use before pregnancy and the days of pregnancy: a cohort study based on propensity score matching. , 2021, 28(6): 658-660.
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