Abstract：Objective To explore the main characteristics and influencing factors of a measles outbreak in a child welfare agencyin Hunan Province, and to analyze the transmission characteristics of the measles outbreak. Methods Retrospective investigation method was used to survey the measles outbreak in a child welfare agency in Hunan Province. The unified questionnaire was employed for conducting the field investigation among the nursing personnel in the child welfare agency. The transmission process was analyzed with the transmission chain diagram and contact history diagram. Results There were 13 confirmed measles cases in the measles outbreak, and all of them were children adopted bythe child welfare agency, with an attack rate being 11.40% in the children. The initial case was hospitalized on day 13 before the onset of illness. The coverage rate of the first-dose measles-containing vaccine (MCV1) in the children of the welfare agency was 42.45% (45/106), while the coverage rate of the second-dose measles-containing vaccine (MCV2) 15.22% (14/92). Multivariate analysis of factors influencing the measles outbreak showed that the risk of measles infection was increased with the increase of time of close contact with measles cases (OR=4.881, 95%CI:1.871 12.735). Conclusions All the secondary cases have the history of close contact with their previous generation, and the close contact among children in the welfare agency and iatrogenic infection are the main factors for the spread of this outbreak. Improving the coverage rate of measles-containing vaccine and strengthening the nosocomial infection control are the key points for controlling measles outbreaks.
2017, Vol. 24 
