Abstract：Objective To study the effect of ginseng-coenzyme Q10 mixed preparations on immunopotentiation. Methods The mice were divided into the low-, medium- and high-dose ginseng-coenzyme Q10 mixed preparation groups (0.083g/kg.bw, 0.167g/kg.bw and 0.500g/kg.bw) respectively, and then they were given ginseng-coenzyme Q10 mixed preparations by gavage for 30 successive days. The control group was intragastrically administered with the same volume of vegetable oil. The changes of immune organs/body weight ratio, cellular immunity and humoral immunity in these mice were observed. Results Compared with the control group, the high-dose ginseng-coenzyme Q10 mixed preparation group could significantly improve delayed type hypersensitivity, the number of antibody-producing cells, HC50 value and NK cell activity (all P<0.05) and showed a dose-dependency. The low-, medium- and high-dose ginseng-coenzyme Q10 mixed preparations showed no obvious effect on body weight gain, thymus/body weight ratio, spleen/body weight ratio, the expurgation and phagocytosis function of monocyte-macrophage,lymphocyte transformation and the number of macrophages swallowing chicken erythrocytes (all P>0.05). Conclusion The results indicate that ginseng-coenzyne Q10 mixed preparations contribute to immunopotentiation.
2017, Vol. 24 
