Abstract:Objective To analyze the epidemiological features of Middle East respiratory syndrome (MERS) cases around the world and reported to the World Health Organization (WHO) in 2015 so as to provide guidance for its prevention and control. Methods We collected the information of MERS cases at home and abroad and reported to the WHO in 2015 from websites of WHO, Saudi Arabia and South Korea, and descriptive epidemiological method was employed for this analysis. Results A total of 12 countries reported 680 laboratory-confirmed MERS cases around the world in 2015, with 237 deaths and the case fatality rate of 34.85%. There were 444 male cases and 236 female ones, respectively accounting for 65.29% and 34.71% of the total reported cases. The median age was 55 years (10 months-109 years old). Most of the reported cases in 2015 were from Saudi Arabia (n=456, 67.06%), followed by South Korea (n=185, 27.21%). South Korea, Philippines, China and Thailand were the countries with a new outbreak in 2015. There were 3 main prevalence peaks in 2015, which mainly caused by clustering outbreaks in medical institutions of South Korea and Saudi Arabia. Conclusions Although aggregation epidemics caused by human-to-human transmission had occurred in families and outbreaks in medical institutions in 2015, a sustained community transmission had not yet appeared. Particular attention should be paid to preventing and controlling the occurrence of outbreaks in hospitals.
[1] Woo PC,Lau SK,Wernery U,et al.Novel betacoronavirus in dromedaries of the Middle East,2013[J].Emerg Infec Dis,2014,20(4):560-572. [2] Haagmans BL,AL Dhahiry SH,Reusken CB,et al. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation[J].Lancet Infect Dis,2014,14(2):140-145. [3] Hemida MG,Chu DK,Poon LL.MERS coronavirus in dromedary camel herd,Saudi Arabia[J].Emerg Infect Dis,2014,20(7):1231-1235. [4] 李群.韩国MERS,人类再次显露阿基里斯之踵[J].中华流行病学杂志,2015,36(8):777-778. [5] 王永怡,王姝,张云辉,等.2015年全球传染病相关热点回顾[J].传染病信息,2016,29(1):30-34. [6] 向妮娟,林丹,安光旭,等.2015年韩国中东呼吸综合征疫情流行病学特征分析[J].中华流行病学杂志,2015,36(8):836-841. [7] 仝振东,王建跃,邬辉,等.中东呼吸综合征流行病学[J].中华流行病学杂志,2015,36(7):765-768. [8] Assiri A,Al-Tawfiq JA,Al-Rabeeah AA, et al.Epidemiological,emographic,and clinical characteristics of 47 cases of Middle East Respiratory Syndrome coronavirus disease from Saudi Arabia:a descriptive study[J].Lancet Infect Dis,2013,3(9):752-761. [9] Drosten C,Meyer B,Marcel A,et al.Transmission of MERS coronavirus in household contacts[J]. N Engl J Med,2014,371(9):828-835. [10] 李毅,孙慧男.中东呼吸综合征冠状病毒的传播与防护[J].中国临床医生杂志,2015,43(1):9-11. [11] Memish ZA,Assiri A,Almasri M,et al. Prevalence of MERS CoV nasal carriage and compliance with the Saudi health recommendations among pilgrims attending the 2013 Hajj[J].J Infect Dis,2014,210(7):1067-1072. [12] Gautret P,Charrel R,Benkouiten S,et al.Lack of MERS coronavirus but prevalence of influenza virus in French pilgrims after 2013 Hajj[J].Emerg Infect Dis,2014,20(4):728-730. [13] Gautret P,Charrel R,Belhouchat K,et al.Lack of nasal carriage of novel corona virus (HCoV-EMC) in French Hajj pilgrims returning from the Hajj 2012, despite a high rate of respiratory symptoms[J]. Clin Microbiol Infect, 2013,19(7):E315-E317. [14] 曾光.2015年中东呼吸综合征与埃博拉病毒病的国际防控[J].国际流行病学传染病学杂志,2016,43(1):1-3. [15] 朱娜,陈涛.韩国中东呼吸综合征(MERS)大爆发: MERS-CoV可持续人际间传播能力是否增强[J].热带病与寄生虫学,2015,13(3):125-126.