Abstract：Objective To investigate the infection status of human T-lymphotropic virus (HTLV) among voluntary blood donors in Changsha, and to provide references for conducting HTLV antibody testing and taking relevant measures in Hunan Blood Center. Methods The routine serological testing was performed among voluntary blood donors in Hunan Blood Center from September to October, 2016; meanwhile, ELISA was used to detect serum HTLV-I/II antibody. And seropositive samples were further confirmed by the National Center for Clinical Laboratories. Sigmaplot drawing software was employed to analyze the distribution of voluntary blood donors from Hunan, the coastal regions like Fujian and Guangdong, and other provinces in Hunan Blood Center during 2010-2016. Results A total of 16,767 blood samples were collected from voluntary blood donors. The preliminary screening was positive in 24 samples, and there were 1 positive sample from Fujian Province, 1 indeterminate sample from Hunan Province and 22 negative samples further confirmed by Western blot. The positive rates of preliminary screening and confirmation were 14.31/10,000 and 5.96/100,000 respectively. The distribution of blood donation population showed that the number of blood donors from Fujian, Guangdong and other coastal regions was more than that from Hunan Province. Conclusions HTLV-Ⅰ/Ⅱ infection is not so prevalent among voluntaryblood donors in Hunan Blood Center, but the proportion of blood donors from Fujian, Guangdong and other high-prevalence coastal regions of HTLV infection increases quickly. It is necessary to conduct HTLV antibody testing and take corresponding measures in Hunan Blood Center so as to ensure blood safety and the health of receptors.
2018, Vol. 25 
