酒依赖与双相障碍共病患者的特征及生活质量综合研究

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摘要目的探究酒依赖与双相障碍共病（comorbid alcohol dependence and bipolar disorder, CADBA）患者的特征以及了解其生活质量。方法选择自2010年10月至2014年5月在浙江萧山医院接受治疗的60例CADBA患者作为本次研究的观察组,以及同期检查正常的健康体检者60例作为对照组。分别应用躁狂自评量表（BRMS）、焦虑自评量表（SAS）、抑郁自评量表（SDS）以及人格障碍临床诊断（SCID-Ⅱ）对观察组和对照组进行特征评定。并采用生活质量综合评定量表（GQOLI-74）对观察组和对照组进行生活质量对比评价。结果观察组患者的BRMS、SAS、SDS、SCID-Ⅱ评分值明显高于对照组,且差异具有统计学意义（P<0.05）;观察组患者的GQOLI-74生活质量综合评分值明显低于对照组,且差异具有统计学意义（P<0.05）。结论CADBA患者的负性情感,如躁狂、抑郁、焦虑、人格障碍等表现突出,且其生活质量明显降低,该表征对 CADBA患者的诊断具有重要的诊断价值。

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	张鹏
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关键词 ：酒依赖与双相障碍共病, 特征, 生活质量

Abstract：Objective:To evaluate characteristics and quality of life for patients with comorbid alcohol dependence and bipolar disorderthe (CADBA) .Methods:60 patients with CADBA accepted treatment in our hospital from October 2010 to May 2014 were selected as the observation group in this study. 60 cases who were considered healthy at the same period as the control group. BRMS、SAS、SDS、SCID-Ⅱwere used to assesse the characteristic of the observation group and control group. To evaluate the characteristic of those by using GQOLI-74.Results:Grade of BRMS、SAS、SDS、SCID-Ⅱin the observation groups were significantly higher than in the control group, the difference was statistically significant (P < 0.05) ; Grade of GQOLI-74 in the observation groups were significantly higher than in the control group, the difference was statistically significant (P < 0.05) .Conclusion:Patients with CADBA have negative emotions, such as mania, depression, anxiety, personality disorder, etc, and the quality of life is obviously decreased. These Characteristics have an important diagnostic value of CADBA.

Key words： Comorbid Alcohol Dependence and Bipolar Disorder Characteristics Quality of Life

作者简介: 张鹏（1980.03.30）,男,浙江杭州萧山人,主治医师,本科,研究方向：酒依赖与双相障碍共病患者的特征及生活质量

引用本文:

张鹏,傅正闯,孟旭. 酒依赖与双相障碍共病患者的特征及生活质量综合研究[J]. 实用预防医学, 2015, 22(7): 829-831. Zhang Peng,Fu Zhengchuang,Meng Xu. Comprehensive Inquiry of Characteristics and Quality of Life for Patients with Comorbid Alcohol Dependence and Bipolar Disorder. , 2015, 22(7): 829-831.

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