Abstract：Objective: To detect human parvovirus B19 IgM,IgG and DNA among women in normal pregnancy and Spontaneous abortion, investigating the prevention and treatment to Spontaneous abortion . Methods: The blood of women in normal pregnancy and Spontaneous abortion are collected, human parvovirus B19 IgM,IgG and DNA are detected with ELISA and PCR. Results: The positive rate of human parvovirus B19 IgM, IgG and DNA were 5.77%,46.15% , 21.15% in Observation group and 0%,63.46%, 3.85% in control group, there was significant difference between two groups(P<0.05) .
引用本文:
胡方兴,孙馨. 微小病毒B19在自然流产患者中的感染状况研究[J]. 实用预防医学, 2015, 22(6): 741-742.
HU Fangxing, SUN Xin. The infection analysis of Human parvovirus B19 among spontaneous aborton in Changsha. , 2015, 22(6): 741-742.
[1] 邵明明,李萍,金春子．孕妇人微小病毒B19 与城乡和季节的关系[J]．中国优生与遗传杂志,2003,11(4)：77． [2] Ergaz Z, Ornoy A. Parvovirus B19 in pregnancy[J]. Reproductive Toxicology, 2006, (21):421-435. [3] Lunardi C, Tinazzi E, Bason C, et al. Human parvovirus B19 infection and 25062222 autoimmunity[J]. Autoimmunity Reviews, 2008,（8）: 116-120. [4] 王净,许桦,窦骏．母婴血细胞人微小病毒B19 感染的检测[J]．实用妇产科杂志,2004,20(4)：218-219． [5] 曹虹,贡树基,赵卫．人微小病毒B19感染的研究进展[J]．微生物学通报,2007,34 (2)：334-338． [6] Jessica T, Brian V. Clinical Presentations of Parvovirus B19 Infection[J]. American Family Physician, 2007, 75（3）: 373-376. [7] Sarfraz AA, Samuelsen SO, Bruu AL, et al. Maternal human parvovirus B19 infection and the risk of fetal death and low birthweight: a case-control study within 35 940 pregnant women[J]. BJOG , 2009, 116: 1492-1498. [8] 袁梦岚,韦业平．人细小病毒B19 与不良妊娠结局的相关性研究[J]．医学研究与教育,2010,27 (1)：89-91. [9] 童顺桃, 黄旭君, 雷慧中．人微小病毒B19宫内感染对妊娠结局的影响[J]．中国妇幼保健,2005,20(20)：2689-2691． [10] Syridou G, Skevaki C, Kafetzis DA,et al. Intrauterine infection with arvovirus B19 and CMV:implications in early and late gestation fetal demise[J].Expert review of anti-infective therapy,2005,3(4):651-653. [11] 袁梦岚．人微小病毒B19与自然流产的关系研究[D]. 中国优秀硕士学位论文全文数据库,2010. [12] 蔡文勤, 张元珍．微小病毒B19与早期自然流产关系的研究[J]．武汉大学学报,2007,28(1)：109-112． [13] Lamont RF, Sobel JD, Vaisbuch E, et al. Parvovirus B19 Infection in Human Pregnancy[J]. BJOG,2011,118(2)：175-186. [14] Elnifro E, Nisha AK, Almabsoot M, et al. Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya[J]. Journal of Infection in Developing Countries, 2009, 3（3）：218-220. [15] De Jong EP, Walther FJ, Kroes AC, et al. Parvovirus B19 infection in pregnancy: new insights and management [J]. Prenat Diagn,2011,31(5)：419-425.
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