Abstract：Objective To explore the characteristics and influencing factors of laboratory-confirmed measles cases in Guangzhou city, to improve the early identification and diagnosis of suspected measles cases, and to provide a scientific basis for measles elimination. Methods Laboratory-confirmed measles cases in 2013-2018 were selected, and then logistic regression analysis was performed to identify the factors influencing these cases. Results A total of 6,310 suspected measles cases were reported in Guangzhou city in 2013-2018, and the blood detection rate of the cases was 93.22%. 2,992 measles IgM-positive patients and 2,370 measles IgM-negative patients were detected in this study. Multivariate logistic regression analysis showed that factors such as gender, age, reporting unit, cough, conjunctivitis, vaccination history of measles-containing vaccine (MCV), and the number of days between rash onset and blood sampling were significantly associated with measles IgM-positive status. Males (OR=1.725, 95%CI:1.139-2.613), populations aged 0-7 months (OR=8.774, 95%CI:1.313-58.614) and 8 months-14 years (OR=12.271, 95%CI:1.907-78.957), cough (OR=3.654, 95%CI:2.201-6.067), conjunctivitis (OR=1.944, 95%CI:1.238-3.052), reporting from tertiary hospitals (OR=5.738, 95%CI:1.471-22.384), having no vaccination with MCV (OR=9.647, 95%CI:2.354-39.530), and conducting blood sampling and detection within 4-28 days after eruption (OR=2.505, 95%CI:1.651-3.800) were risk factors for laboratory-confirmed measles IgM-positive cases. Conclusions Collecting suspected measles cases’ general information, clinical symptoms and history of immunization is conducive to early identification and diagnosis of measles cases. At the same time, routine vaccination among high-risk population without MCV vaccination history should be strengthened in the critical period of measles elimination, and diagnosis level of clinicians should be improved.
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2020, Vol. 27 
