Abstract:Objective To analyze the influenza surveillance data about children aged 0-14 years in Henan province from 2014 to 2018 and the current status of influenza vaccination in the province, and to provide scientific evidence for influenza prevention in children. Methods Based on the National Influenza Surveillance Network, we collected and analyzed the data regarding 0-14-year-old children's influenza like illness (ILI) cases and virologic detection results reported by 22 sentinel hospitals in Henan province from September 2014 to August 2018; meanwhile, we analyzed influenza vaccination on the basis of the data collected from the Information Management System of Immunization Program in Henan Province and concerning influenza vaccination of children aged 0-14 years from September 2014 to August 2018. Results The number and proportion of ILI cases of children aged 0-14 years in Henan province in the four monitoring years from 2014 to 2018 were 129,905 (79.97%), 135,148 (79.56%), 142,653 (80.88%) and 181,760 (81.77%), respectively. The popular strains in 2014-2016 were mainly the H3 subtype and B type. The popular strains in 2017-2018 were mainly the H1N1 type A, interlacing with the H3 and B type Yamagata lines. The positive rate of influenza virus showed an upward trend with the increase of children's age, and the difference was statistically significant (χ2trend=1,244.06, P<0.001). Influenza occurring in younger children aged 0-8 years was mainly concentrated in winter (69.42%), spring (15.86%) and autumn (13.57%), while that occurring in elder children age 9-14 years in winter (76.17%) and autumn (14.82%). Influenza vaccination for children aged 0-14 years in Henan province in 2014-2018 began in August and reached a peak in October, with the amount of influenza vaccination from July to October accounting for 36.09% of the total inoculation. Conclusions The peak of children influenza epidemic in Henan province in 2014-2018 is mainly in winter, and the predominant strains circulate alternately. Special attention should be paid to the impact of influenza A virus on children. On the basis of prevention and control of influenza in autumn and winter, influenza prevention and control in preschoolers in spring should be further strengthened. Influenza vaccination for children in Henan province is late; and hence, it is recommended that full-course influenza vaccination for children should be completed before October.
王长双, 姬艳芳, 赵升, 僧明华, 路明霞, 徐瑾, 叶莹, 张延炀. 河南省2014—2018年度儿童流感流行特征与疫苗接种现状分析[J]. 实用预防医学, 2020, 27(5): 569-571.
WANG Chang-shuang, JI Yan-fang, ZHAO Sheng, SENG Ming-hua, LU Ming-xia, XU Jin, YE Ying, ZHANG Yan-yang. Epidemic characteristics and vaccination status of childhood influenza in Henan province, 2014-2018. , 2020, 27(5): 569-571.