Abstract：Objective To study the epidemiological features and genotypes of human astrovirus (HastV) in young children with diarrhea in Lulong County. Methods Fecal specimens were collected from children with diarrhea under 5 years of age hospitalized in the Children’s Hospital of Lulong County and Maternal and Child Health Hospital of Lulong County from 2010 to 2014. HastV was tested by RT-PCR, some PCR-positive samples were sequenced, and then the genotypes were identified. Results HastV was detected in 47 of 1,880 specimens, with the detection rate of 2.5%. The age of the inflicted children ranged from 0 to 47 months, and 87.2% of the children were younger than 24 months. Most of the cases occurred in winter, the positive detection rates were found to be higher from February to May (4.23%-5.61%). Some PCR amplicons sequenced were identified to be HastV-1. Conclusions HastV is an important etiologic agent contributing to diarrhea in young children in Lulong County in 2010-2014. An obvious trend of high prevalence in the cold season is present, and HastV-1 is the local prevalent strain.
于秋丽， 刘莹莹， 赵文娜， 谢赟， 苏通， 齐顺祥. 2010-2014年卢龙县5岁以下婴幼儿腹泻星状病毒流行特征分析[J]. 实用预防医学, 2017, 24(1): 52-54.
YU Qiu-li, LIU Ying-ying, ZHAO Wen-na, XIE Yun, SU Tong, QI Shun-xiang. Epidemiological characteristics of astrovirus induced diarrhea in children under 5 years old in Lulong County, 2010-2014. , 2017, 24(1): 52-54.
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