Hospital-based monitoring data of perinatal birth defects in Hunan Province, 2007-2016
XIE Qiong*, TAN Hong-zhuan, QIN Jia-bi, XIE Dong-hua, LIU Zhi-yu, WANG Hua
*Xiangya School of Public Health, Central South University, Changsha, Hunan 410078, China; Hunan Provincial Matenal and Child Health Care Hospital, Changsha, Hunan 410008, China
Abstract：Objective To analyze the prevalence of birth defects in Hunan Province from 2007 to 2016 so as to provide a scientific basis for future prevention and intervention of birth defects. Methods According to the requirement of China Maternal and Child Health Monitoring Program, the data were collected from 53 monitoring hospitals for birth defects in Hunan, and were statistically analyzed by SPSS 19.0 software. Results A total 1,177,050 perinatal infants were monitored from 2007 to 2016. Birth defects were found in 22,548 perinatal infants,and the average incidence rate of birth defects during the period of 10 years was 191.56/10,000. The incidence rate had continuously risen since 2007, reached its peak in 2011 (227.81/10,000), and then showed a downward trend and decreased to the lowest point (149.40/10,000)in 2016. The incidence rate of birth defects was higher in urban areas (213.36/10,000) than in rural ones (173.19/10,000). Mothers aged above 35 or below 20 years were vulnerable to giving birth to infants with birth defects. The major birth defects included congenital heart disease, multi-finger (toe), kidney deformities, other deformities of the external ear, total cleft lip,syndactyly, clubfoot, hypospadias, limb shortening, and rectal anal atresia or stenosis. Conclusions Prevention and control of birth defects is still an arduous task in Hunan Province. Tertiary prevention strategy of birth defects should be performed in pre-marital, pre-pregnancy, pregnancy and neonatal stages.
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2017, Vol. 24 
