Abstract：Objective To analyze the factors influencing thyroid volume of children aged 8-10 years in Xiamen City, and to provide a scientific basis for scientifically evaluating the prevention and treatment effect of iodine deficiency disorders and adjusting the evaluation index of thyroid volume. Methods We recruited 8-10-year-old non-boarding students from one primary school each selected in each east, west, south, north and middle part of each district in the six districts of Xiamen City. Random urine samples, salt samples at home, thyroid volume, height and body weight were collected once. Results A total of 1,259 children aged 8-10 years in Xiamen City were selected, including 627 boys, 632 girls, 423 children aged 8 years, 419 children aged 9 years and 417 children aged 10 years. The median urinary iodine was 164.58 ug/L, the median salt iodine 24.02 ug/L, the coverage rate of iodized salt 93.01%, and the consumption rate of qualified iodized salt 91.47%. There were 33 children with goiter, with the goiter rate being 2.62%. The thyroid volume was independent of sex (Z=-0.736, P=4.602), but increased with age, height, body weight, body mass index and body surface area (Spearman correlation coefficients were 0.30, 0.41, 0.44, 0.31 and 0.47 respectively, and the partial correlation coefficients were 0.80, 0.13, 0.25, -0.03 and 0.18 respectively). The standard partial regression coefficients of age, height, body surface area and body weight were 0.09, 0.10, 0.15 and 0.23 respectively, and the ratio of them was 1∶1.22∶1.75∶2.71. Conclusions The thyroid volume of children in Xiamen City is influenced by many factors, and the influence of height, weight and body surface area should be considered besides age when evaluating the children’s thyroid volume.
2023, Vol. 30 
