Abstract：Objective To investigate the distribution characteristics and changes of pathogenic bacteria in inpatients with AIDS in a hospital of Changsha City in recent 5 years. Methods BioMerieux ATB New 1.1 beta statistic software was used to retrospectively analyze the identification results of pathogenic bacteria isolated from blood and cerebrospinal fluid (CSF) of AIDS inpatients in a hospital in Changsha City from 2010 to 2014.Results The positive rates of pathogenic bacteria from blood and CSF cultures of the AIDS inpatients were 10.81% and 2.90% in 2010, 17.90% and 5.14% in 2011, 19.36% and 3.67% in 2012, 14.37% and 3.00% in 2013 and 17.28% and 4.13% in 2014. There were statistically significant differences in the positive rates of pathogenic bacteria from blood cultures among different years ( χ 2=16.23, P <0.05), but no statistically significant differences were found in the positive rates of pathogenic bacteria from CSF cultures among different years ( χ 2=4.97, P >0.05). The top 3 pathogenic bacteria from blood cultures were Penicillium marneffei （49.68%-58.26%）, Cryptococcus neoformans （10.06%-18.39%）and Staphylococcus spp. (14.68-30.82%). The top 2 pathogenic bacteria from CSF cultures were Cryptococcus neoformans and Staphylococcus spp.. Among the pathogenic bacteria from blood and CSF cultures, the proportion of Staphylococcus spp. fluctuated significantly, but no an upward trend and no statistically significant differences were found during 2010-2014 ( χ 2=9.38, P=0.05; χ 2= 2.42, P >0.05). Conclusions The main pathogenic bacteria from blood and CSF cultures of the AIDS inpatients in this hospital in Changsha City during 2010-2014 are fungi and Staphylococcus spp., but the others show a sporadic distribution. The positive rates of pathogenic bacteria in 2010-2014 present a certain range of fluctuation, without showing an obvious increase or descent tendency year by year.
何红, 徐丹, 沈辉, 黄维亮, 郭婷, 邹明祥. 2010-2014年长沙市某医院AIDS住院患者感染菌群分布[J]. 实用预防医学, 2017, 24(2): 202-204.
HE Hong, XU Dan, SHEN Hui, HUANG Wei-liang, GUO Ting, ZOU Ming-xiang. Distribution of pathogenic bacteria in AIDS inpatients in a hospital of Changsha City, 2010-2014. , 2017, 24(2): 202-204.
2017, Vol. 24 
