Abstract：Objective To analyze the pathogenic surveillance results of influenza in Yunfu City during 2010-2014, to summarize the epidemic pattern of influenza so as to provide a scientific basis for prevention and control of influenza epidemics. Methods Nasopharyngeal swab specimens were weekly collected from influenza-like cases in the influenza sentinel hospitals. Influenza viruses were isolated by Madin-Darby canine kidney (MDCK) cells, and the nucleic acid of the viruses was detected by Real-time PCR. Subtypes were identified by hemagglutination inhibition (HI) test or Real-time PCR. Results A total of 11,723 nasopharyngeal swab specimens were collected from 2010 to 2014, and 986 were identified as influenza positive, with the positive rate of 8.4%. The positive detection rates in each year were 9.6%, 1.6%, 10.5%, 4.7%, 12.7% and 8.4% respectively, with statistically significant differences (χ2=231.61, P=0.00). Among the positive specimens, A1 (H1N1), A3 (H3N2), A (H1N1) pdm, B (Victoria) and B (Yamataga) accounted for 0.4% (4/986), 36.8% (363/986), 27.1% (267/986), 22.9% (226/986) and 12.8% (126/986) respectively. There were statistically significant differences in the positive detection rates among the age groups of 0- year, 5-, 15-, 25- and >60 years (χ2=104.5, P=0.00). The detection peaks of influenza appeared from March to September in 2010, from January to March in 2012, from March to June and December in 2013. There were 2 peaks in 2014, one from January to April and another from June to July. Conclusions Influenza outbreaks in Yunfu City are mainly mixed epidemics, and the predominant strains of influenza viruses in each year are different. Influenza activity shows seasonal characteristics and is strong from January to July. There are 2 epidemic peaks, one in winter-spring and another in summer.
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2016, Vol. 23 
