Abstract：Objective To investigate the epidemiological characteristics of severe hand, foot and mouth disease (HFMD) in Chengdu City so as to provide evidence for focus prevention and control of HFMD in local areas. Methods Descriptive epidemiological method was used to analyze the time, region and population distribution features and pathogenic characteristics of severe HFMD cases in Chengdu City from 2011 to 2014. Results A total of 1,189 severe HFMD cases (including laboratory-confirmed cases (61.56%) and death cases (0.67%)) were confirmed by the Network Direct Report System of Infectious Disease Epidemics and the case surveillance in Chengdu City from January 2011 to December 2014. 97.31% of the severe cases occurred in children aged <5 years. The male to female ratio of the severe cases was 1.541. Most of the severe cases were scattered children and preschoolers, and the incidence peak occurred during April-July. The severe cases were mainly detected in Longquanyi District, Wuhou District, Jinniu District, Chenghua District, Shuangliu County and Jinjiang District. The major pathogens of the laboratory-confirmed severe cases were EV71 (40.03%), Cox A16 (4.92%) and other enteric virus (55.05%). Conclusions The severe HFMD cases mainly occur in children aged < 5 years, and the incidence is higher in males than in females. Spring and summer are the main onset seasons. The incidence rates of the severe HFMD cases in Chengdu City during 2011-2014 present a tendency of declining first and then increasing. The highest incidence rate is found in 2013, and the incidence intensity varies obviously with different areas, which may be attributed to the population density and mobility factors in these areas.
郭正梅, 速丽媛, 杨才彬, 薛毅, 蒋晓兰. 2011-2014年成都市手足口病重症病例流行病学分析[J]. 实用预防医学, 2016, 23(12): 1499-1502.
GUO Zheng-mei, SU Li-yuan, YANG Cai-bin, XUE Yi, JIANG Xiao-lan. Epidemiological analysis on severe cases of hand, foot and mouth disease in Chengdu City, 2011-2014. , 2016, 23(12): 1499-1502.
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2016, Vol. 23 
