Abstract:Scan statistic is an effective method used in spatial epidemiology to evaluate or predict disease aggregation. More and more researchers use this method to study the aggregation of tuberculosis and its influencing factors and reveal the distribution and transmission regularity of tuberculosis from space perspective. Scan statistic has an extensive application prospect in the prediction of tuberculosis outbreak, and combining scan statisticwith the genotyping results ofMycobacterium tuberculosis can also detect the regional spread, recent transmission and transmission chain. At present, it is still an important subject worthy of further study in China. This paper describes the basic concept, method and principle of scan statistic and the current application status in tuberculosis.
[1] Murray CJ, Ortblad KF, Guinovart C, et al.Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013:a systematic analysis for the Global Burden of DiseaseStudy 2013[J].Lancet, 2014,384(9947):1005-1070. [2] 康万里, 郑素华.空间扫描统计在中国菌阳结核病分布中的应用[J].中国卫生统计, 2012,29(4):487-489. [3] 唐益, 龚德华, 白丽琼.湖南省2003_2011年活动性肺结核患者登记的空间分析[J].中国防痨杂志, 2012,34(12):764-767. [4] 李秀央, 陈坤.扫描统计量的理论及其在空间流行病学中的应用[J].中华流行病学杂志, 2008,29(8):828-831. [5] Nunes C.Tuberculosis incidence in Portugal:spatiotemporal clustering[J].Int J Health Geogr, 2007,6:30. [6] Zaragoza BA, Hernandez TM, Bustamante ML, et al.Spatial and temporal distribution of tuberculosis in the State of Mexico, Mexico[J].Sci World J, 2012,2012:570278. [7] Tadesse T, Demissie M, Berhane Y, et al.The clustering of smear-positive tuberculosis in Dabat, Ethiopia:a population based cross sectional study[J].PLoS One, 2013,8(5):e65022. [8] Zhao F, Cheng S, He G, et al.Space-time clustering characteristics of tuberculosis in China, 2005-2011[J].PLoS One, 2013,8(12):e83605. [9] Wang T, Xue F, Chen Y, et al.The spatial epidemiology of tuberculosis in Linyi City, China, 2005-2010[J].BMC Public Health, 2012,12:885. [10] Dangisso MH, Datiko DG, Lindtjorn B.Spatio-temporal analysis of smear-positive tuberculosis in the Sidama Zone, southern Ethiopia[J].PLoS One, 2015,10(6):e126369. [11] Tiwari N, Adhikari CM, Tewari A, et al.Investigation of geo-spatial hotspots for the occurrence of tuberculosis in Almora district, India, using GIS and spatial scan statistic[J].Int J Health Geogr, 2006,5:33. [12] Rakotosamimanana S, Mandrosovololona V, Rakotonirina J, et al.Spatial analysis of pulmonary tuberculosis in Antananarivo Madagascar:tuberculosis-related knowledge, attitude and practice[J].PLoS One, 2014,9(11):e110471. [13] Randremanana RV, Sabatier P, Rakotomanana F, et al.Spatial clustering of pulmonary tuberculosis and impact of the care factors in Antananarivo City[J].TM & IH, 2009,14(4):429-437. [14] Oren E, Narita M, Nolan C, et al.Neighborhood socioeconomic position and tuberculosis transmission:a retrospective cohort study[J].BMC Infect Dis, 2014,14:227. [15] Mills HL, Cohen T, Colijn C.Modelling the performance of isoniazid preventive therapy for reducing tuberculosis in HIV endemic settings:the effects of network structure[J].J R Soc Interface, 2011,8(63):1510-1520. [16] Prussing C, Castillo-Salgado C, Baruch N, et al.Geo-epidemiologic and molecular characterization to identify social, cultural, and economic factors where targeted tuberculosis control activities can reduce incidence in Maryland, 2004-2010[J].Public Health Rep, 2013,128(Suppl 3):104-114. [17] Li T, He XX, Chang ZR, et al.Impact of new migrant populations on the spatial distribution of tuberculosis inBeijing[J].Int J Tuberc Lung Dis, 2011,15(2):163-168. [18] 路丽苹, 洪建军, 高谦, 等.上海松江2006-2011年新登记肺结核时空分布规律及影响因素[J].中华疾病控制杂志, 2014,18(8):709-714. [19] Haase I, Olson S, Behr MA, et al.Use of geographic and genotyping tools to characterise tuberculosis transmissionin Montreal [J].Int J Tuberc Lung Dis, 2007,11(6):632-638. [20] Moonan PK, Ghosh S, Oeltmann JE, et al.Using genotyping and geospatial scanning to estimate recent mycobacterium tuberculosis transmission, United States[J].Emerg Infect Dis, 2012,18(3):458-465. [21] Baker BJ, Moonan PK.Characterizing tuberculosis genotype clusters along the United States-Mexico border [Short communication][J].Int J Tuberc Lung Dis, 2014,18(3):289-291. [22] 刘媛, 王学高, 刘美伶.江苏省阜宁县活动性肺结核病患者分子成簇与空间聚集研究[J].中华传染病杂志, 2013,31(8):449-453. [23] Ricks PM, Cain KP, Oeltmann JE, et al.Estimating the burden of tuberculosis among foreign-born persons acquired prior to entering the U.S., 2005-2009[J].PLoS One, 2011,6(11):e27405. [24] Kammerer JS, Shang N, Althomsons SP, et al.Using statistical methods and genotyping to detect tuberculosis outbreaks[J].Int J Health Geogr, 2013,12(1):15. [25] Althomsons SP, Kammerer JS, Shang N, et al.Using routinely reported tuberculosis genotyping and surveillance data to predict tuberculosis outbreaks[J].PLoS One, 2012,7(11):e48754. [26] Tiwari N, Kandpal V, Tewari A.Investigation of tuberculosis clusters in Dehradun city of India[J].Asian Pac J Trop Med, 2010:486-490. [27] 山珂.肺结核发病空间聚集分布及影响因素研究[D].济南:山东大学, 2014. [28] 殷菲, 李晓松, 冯子健, 等.前瞻性时空扫描统计量在传染病早期预警中的应用[J].中华预防医学杂志, 2007,41(增刊):155-158. [29] 殷菲, 冯子健, 李晓松, 等.基于前瞻性时空重排扫描统计量的传染病早期预警系统[J].卫生研究, 2007,36(4):455-458. [30]Touray K, Adetifa I, Jallow A.Spatial analysis of tuberculosis in an urban west African setting:is there evidence of clustering[J].Trop Med Int Health, 2010,15(6):664-672. [31] 金瑾.2010-2012年济宁市肺结核空间流行病学研究[D].济南:山东大学, 2014. [32] Hassarangsee S, Tripathi N, Souris M.Spatial pattern detection oftuberculosis: a case study ofSiSa KetProvince, Thailand[J].Int J Environ Res Public Health, 2015,12(12):16005-16018.