Determination of eugenol anesthetics and their metabolites in water by gas chromatography-mass spectrometry
PI Chao-fan1, ZHANG Xin-qi1, LIU Feng1, LI Tan-yao2
1. Yiyang Municipal Center for Disease Control and Prevention, Yiyang, Hunan 413000, China; 2. Hunan Provincial Center for Disease Control and Prevention, Changsha, Hunan 410005, China
Abstract：Objective To develop an analytical method based on gas chromatography-mass spectrometry (GC-MS) for determination of eugenol anesthetics and their metabolites in water. Methods The analytes were enriched firstly by HLB solid phase extraction column, then eluted with ethyl acetate, and finally determined by GC-MS. Results The detection limit of the method was 0.01 μg/L. The recoveries of eugenol and related substances were 78.6%-104%, and the relative standard deviations were less than or equal to 7.0% (n=5). Conclusion The method is sensitive and accurate, and can be used to detect the contamination of eugenol fish anesthetics and their major metabolites in environmental water.
皮超凡, 章新奇, 刘峰, 李谭瑶. 气相色谱-质谱法测定水中丁香酚类麻醉剂及其代谢物的研究[J]. 实用预防医学, 2022, 29(9): 1089-1092.
PI Chao-fan, ZHANG Xin-qi, LIU Feng, LI Tan-yao. Determination of eugenol anesthetics and their metabolites in water by gas chromatography-mass spectrometry. , 2022, 29(9): 1089-1092.
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2022, Vol. 29 
