Abstract：Objective To study the relationship of waist circumference and waist-to-height ratio with brachial-ankle pulse wave velocity, and to explore the influence of abdominal obesity on peripheral artery elasticity. Methods We selected 2,718 health check-up subjects from Physical Examination Center, the First Affiliated Hospital of China Medical University from March 2018 to May 2019. Arteriosclerosis tester was used to detect baPWV in bilateral limbs. Based on the results of baPWV, they were divided into the normal group and the elevated group. The values of waist circumference, waist-to-height ratio, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP) and biochemistry indexes were simultaneously detected. t test was used to compare the differences in the above-mentioned indexes between the two groups. Multifactor logistic regression analysis was applied to identifying the factors influencing baPWV, and ROC curve was employed to determine the predictive values of waist circumference and waist-to-height ratio on baPWV. Resultst test showed that the values of male ratio, age, waist circumference, waist-to-height ratio, BMI, SBP, DBP, fasting blood glucose (FBG), triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and uric acid (UA) in the elevated group were all significantly higher than those in the normal group (all P<0.01). Multifactor logistic regression analysis revealed that waist circumference (OR=0.938, 95%CI: 0.884-0.995), waist-to-height ratio (OR=1.605, 95%CI: 1.486-1.804), BMI (OR=0.881, 95%CI: 0.796-0.975) were the independent factors influencing baPWV. The optimal cut-off point of waist circumference to value increased baPWV was 80.50 cm, and the area under ROC curve was 0.725, with the sensitivity and specificity being 0.854 and 0.483, respectively. The best cut-off point of waist-to-height ratio to value increased baPWV was 0.495, and the area under ROC curve was 0.762, with the sensitivity and specificity being 0.814 and 0.548, respectively. Conclusion The elevated values of waist circumference and waist-to-height ratio were the independent factors influencing elevated baPWV, and could predict the occurrence of peripheral arterial stiffness.
王鑫, 王巍, 张君丞. 腰围、腰高比与肱踝脉搏波传导速度的相关性研究[J]. 实用预防医学, 2021, 28(7): 791-794.
WANG Xin, WANG Wei, ZHANG Jun-cheng. Correlation of waist circumference and waist-to-height ratio with brachial-ankle pulse wave velocity. , 2021, 28(7): 791-794.
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