Abstract：Tuberculosis is a chronic infectious disease that causes by Mycobacterium tuberculosis infection, which is type IV hypersensitivity mediated by T lymphocyte and one of the major infectious diseases of public health. A hot study of tubercular immunology is the change of cytokine and the cytokine gene polymorphism with susceptibility to tuberculosis. Studies show that the levels of cytokines in pulmonary tuberculosis patients with anti-tuberculosis therapies can change, and the cytokine gene replacement can increase the infection rate of pulmonary tuberculosis. The occurrence, development and treatment of pulmonary tuberculosis are closely related to human immunity; and hence, exploring the changes of cytokines in patients with pulmonary tuberculosis has an important significance in monitoring its progression and estimating its prognosis. This article summarizes the changes of cytokines in pulmonary tuberculosis patients in recent years.
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2016, Vol. 23 
