Abstract：Objective To analyze the epidemiological features of patients with drug-resistant and non-drug-resistant tuberculosis in Shunde region. Methods Questionnaire survey on the diagnosis, patients’ general information, the present and the past medical records was conducted among 706 patients with smear-positive pulmonary tuberculosis in Shunde region from January 2014 to October 2015. The data were entered into the Excel, and then statistically analyzed. Results Among 706 research subjects, the total drug resistance of pulmonary tuberculosis was 30.88% (218/706). 700 qualified questionnaires were retrieved, including 483 cases of non-drug-resistant tuberculosis and 217 cases of drug-resistant tuberculosis. There were statistically significant differences in the educational background, postponing visiting doctor and complicating with chronic diseases between drug-resistant tuberculosis group and non-drug-resistant tuberculosis (P<0.05). The proportion of re-treated patients (26.3%), the proportion of patients with lesions involving the lung field ≥ 3 (52.5%) and the proportion of patients with intrapulmonary cavity (30.4%) in drug-resistant group were all higher than those of non-drug-resistant group, while the proportion of patients completing the first course of anti-TB treatment in drug-resistant group was lower than that of non-drug-resistant group (65.4% vs. 91.9%), and the differences were statistically significant (both P<0.05). Conclusions The re-treatment rate and the drug resistance rate of pulmonary tuberculosis patients in Shunde region are high. The key points to reduce the occurrence of drug-resistant tuberculosis are to enhance the propaganda about TB prevention and treatment in local region, especially in the group with poor educational background, to let the TB patients timely visit the doctor, to improve the complete rate of first course of anti-TB treatment and to reduce the number of re-treatment patients.
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2016, Vol. 23 
